BIO 435 BIO 435
ENZYMOLOGY ENZYMOLOGY
XII. WEEK
REGULATORY ENZYMES
1. Allosteric enzymes undergo
conformational
changes in response to modulator
binding.
2. In many pathways, a
regulated step is catalyzed by an allosteric enzyme.
3. The kinetic properties of
allosteric enzymes differ from the
Michaelis-Menten behavior.
4. Some regulatory enzymes undergo reversible covalent
modification.
5. Phosphoryl groups affect the structure
and catalytic
activity of proteins.
6. Multiple
phosphorylations provide regulatory
control.
7. Some enzymes are regulated by
the proteolytic cleavage of an
enzyme precursor.
