BIO 405 BIO 405
ENZYMOLOGY ENZYMOLOGY
II. WEEK
REGULATION OF
CATALITIC ACTIVITY AND ENERGY
CONVERSION
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
SIMPLE ENZYME
CONJUGATED ENZYME
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
APOENZYME
HOLOENZYME
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
PROSTETIC GROUPS Coenzyme
Cofactors
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
ENZYME
SUBSTRATE
ENZYM-SUBSTRATE COMPLEX
PRODUCT
ACTIVE ZONE
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
REACTIONS
DEHYDRATION: SYNTHESIS HYDROLYSIS:
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
REACTIONS
ANABOLIC REACTIONS CATABOLIC REACTIONS
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
REACTIONS
EXERGONIC REACTIONS ENDERGONIC REACTIONS
ENZYME TERMINOLOGY ENZYME TERMINOLOGY
• Basic state
Transition state
Turnover count (kcat)
CATALYST CATALYST
Reduces the amount of energy to start a reaction…
ENZYMES ENZYMES
Biological catalysts
Protein structure (& RNA)
Facilitates chemical reactions Increases reaction speed and
reduces activation energy without consuming
Required for biological reaction Highly specific
Thousands of different numbers Control reactions of life
ACTIVATION ENERGY ACTIVATION ENERGY
ENZYMES AFFECT THE REACTION.
They increase the reaction rate by lowering the
activation energy.
