Çalışma verileri, serum H-FABP düzeyinin elektrik çarpması sonrası erken ölümlerde tanısal değer taşıyabileceğine yönelik bakış açımızı desteklemektedir.
Ancak bu bakı klinik ve H-FABP’ın post mortem değişimini ortaya koyan kontrollü çalışmalar ile desteklenmelidir.
Troponin I, elektrik çarpması sonrasında bir süre yaşayan olgularda zamanla artan serum değeri ile tanısal değer taşıyabilir. Ancak bu çıktı, klinik çalışmalar ile desteklenmelidir.
56
KAYNAKLAR
1. Knight B, Saukko PJ. Knight’s forensic pathology (3rd ed). Arnold, London 2004.
2. DiMaio VJ, DiMaio D. Forensic pathology (2nded). CRC Press, New York 2001.
3. Cohle SD, Sampson BA. The negative autopsy: sudden cardiac death or other. Cardiovasc Pathol 2001;10:219-22.
4. Koop J, Loos B, Spilker G, Hocrh RE. Correlation between serum creatinine kinase levels and extent of muscle damage in electrical burns. Burns 2004;30:680-3.
5. Fineschi V, Donato SD, Mondillo S, Turillazzi E. Electric shock: cardiac effects relative to non fatal injuries and post-mortem findings in fatal cases.
Int J Cardiol 2006;111:6-11.
6. Suzuki M. Hori S, Noma S, Kobayashi K. Prognostic value of a qualitative test for heart-type fatty acid-binding protein in patients with acute coronary syndrome. Int Heart J 2005;46:601-6.
7. Khalifa AB, Najjar M, Addad F, Turki E, Mghirbi T. Cardiac troponin T (cTn T) and the postmortem diagnosis of sudden death. Am J Forensic Med Pathol 2006;27:175-7.
8. Osuna E, Perez-Carceles MD, Alvarez MV, Noguera J, Luna A. Cardiac troponin I (cTn I) and the postmortem diagnosis of myocardial infarction. Int J Legal Med 1998;111:173-6.
9. Seino Y, Ogata K, Takano T, et al. Use of a whole blood rapid panel test for heart-type fatty acid-binding protein in patients with acute chest pain:
comparison with rapid troponin T and myoglobin tests. Am J Med 2003;115:185-90.
10. Mileaf H. Electricity One-Seven (revised 2nd ed). Hayden Book Company, New Jersey 1976.
57
11. Nabours RE. An Introduction to Basic Electrical Systems. In: Nabours RE, Fish RM, Hill PF (eds) Electrical Injuries: Engineering, Medical and Legal Aspects (2nd ed). Lawyers & Judges Publishing Company, Tucson 2004.
12. Bishop O. Electronics: A First Course (2nd ed). Elsevier Science &
Technology, Oxford 2006.
13. Price TG, Cooper MA. Electrical and lightning injuries. In: Marx JA, Hockberger RS, Walls RM, et al (eds). Rosen’s Emergency Medicine:
Concepts and Clinical Practice (7th ed). Mosby, China 2010, pp. 1893-1902.
14. Spies C, Trohman RG. Narrative review: Electrocution and life-threatening electrical injuries. Ann Intern Med 2006;145:531-7.
15. Dzhokic G, Jovchevska J, Dika A. Electrical Injuries: Etiology, Pathophysiology and Mechanism of Injury. Maced J Med Sci 2008;1(2):54-8.
16. DeBono R. A histological analysis of a high voltage electric current injury to an upper limb. Burns 1999;25:541-7.
17. Bryan BC, Andrews CJ, Hurley RA, Taber KH. Electrical Injury Part I:
Mechanisms. J Neuropsychiatry Clin Neurosci 2009:21(3);241-4.
18. Chen W, Wu W. Electric field-induced changes in membrane proteins charge movement currents. Burns 2006;32:833-41.
19. Lee RC. Cell injury by electric forces. Ann NY Acad Sci 2005;1066:85-91.
20. Bhatt DL, Gaylor DC, Lee RC. Rhabdomyolysis due to pulsed electric fields.
Plast Reconstr Surg 1990;86:1-11.
21. Shkrum MJ, Ramsay DA. Forensic pathology of trauma:common problems for the Pathologist. Humana Press, Totowa New Jersey 2007.
22. Koumbourlis AC. Electrical injuries. Crit Care Med 2002;30(11Suppl);424-30.
23. Marc B. Electric shocks and electrocution, clinical effects and pathology.
Encyclopedia of Forensic and Legal Medicine. Elsevier Academic Press, Boston 2005, pp. 259-63.
24. Wick R, Byard RW. Electrocution and the Autopsy. In Tsokos M. (ed), Forensic pathology reviews (vol 5) Humana Press, USA 2008, pp. 53-66.
25. Dega S, Gnaneswar SG, Rao PR, Ramani P, Krishna DM. Electrical burn injuries. Some unusual clinic and management. Burns 2007;33(5):653-65.
26. Ritenour AE, Morton MJ, McManus JG, Barillo DJ, Cancio LC. Lightning injury: A review. Burns 2008;34:585-94.
58
27. Gutierrez JG, Melendez J, Torrero JV, Obregon O, Uceda M, Gabilondo FJ.
Lightning injuries in a pregnant woman: a case report and review of the literature Burns 2005;31:1045-49.
28. Dawson TW, Caputa K, Stuchly MA, Kavet R. Electric fields in the human body resulting from 60-Hz contact currents. IEEE Trans Biomed Eng 2001;48(9):1020-6.
29. Tarao H, Hayashi N, Isaka K. Heart current in an anatomically realistic human model due to contact with a low-frequency energized source. IEEJ Trans 2009;4:306-8.
30. Jain S, Bandi V. Electrical and lightning injuries. Crit Care Clin 1999;15:319-31.
31. Bikson M. A Review of hazards associated with exposure to low voltage.
Available from
http://bme.ccny.cuny.edu/faculty/mbikson/BiksonMSafeVoltage Review.pdf;
son erişim tarihi:30.07.2011.
32. Cherington M. Neurologic manifestations of lightning strikes. Neurology 2003;60:182-5.
33. Oehmichen M, Auer RN, König HG. Forensic neuropathology and neurology.
Springer Verlag, Berlin Heidelberg 2006.
34. Martinez JA, Nguyen T. Electrical injuries. South. Med. J 2000;93:1165-8.
35. Masanes MJ, Gorbiere E, Prudent J. A high voltage electrical burn of lung parenchyma. Burns 2000;26:659-63.
36. Buechner HA, Rothbaum JC: Lightning stroke injury: a report of multiple casualties from a single lightning bolt, Mil Med 1961;126:755-62.
37. Solterman B, Frutiger A, Kuhn M. Lightning injury with lung bleeding in a tracheotomized patient, Chest 1991;99:240-2.
38. Soysal Z, Çakalır C. Adli Tıp. İstanbul Üniversitesi Basımevi, İstanbul 1999.
39. Rangaraj R, Moorthy N, Patil SS, Manjunath CN. Brugada-type Electrocardiographic Pattern Induced by Electrocution. Indian Pacing Electrophysiol J 2009;9(1):56-9.
40. Ku CS, Lin SL, Hsu TL, Wang SP, Chang MS. Myocardial damage asso-ciated with electrical injury. Am Heart J 1989;118:621-4.
41. Kinney TJ. Myocardial infarction following electrical injury. Ann Emerg Med 1982;11:622-5.
59
42. Vedung S, Arturson G, Wadin K, Hedlund A. Angiographic findings and need for amputation in high tension electrical injuries. Scand J Plast Reconstr Surg Hand Surg 1990;24:225-31.
43. Koshima I, Moriguchi T, Soeda S, Murashita T. High-voltage electrical injury: electron microscopic findings of injured vessel, nerve, and muscle.
Ann Plast Surg 1991;26:587-91.
44. Moncrief JA, Pruitt BA Jr. Electric injury. Postgrad Med 1970;48:189-94.
45. Rouse RG, Dimick AR. The treatment of electrical injury compared to burn injury: a review of pathophysiology and comparison of patient management protocols. J Trauma 1978;18:43-7.
46. Butler ED, Gant TD. Electrical injuries, with special reference to the upper extremities. A review of 182 cases. Am J Surg 1977;134:95-101.
47. Newsome TW, Curreri PW, Eurenius K. Visceral injuries: An unusual complication of an electrical burn. Arch Surg 1972;105:494-7
48. Cooper PN. Burn injury. In: Ruty Gn (ed.) Essentials of Autopsy Practise:
Current methods and modern trends. Springer-Verlag, London 2006, pp.215-32.
49. Akyıldız AÜ. Elektrik Akımı Lezyonlarında Histopatolojik Bulgular. Türkiye Klinikleri J Foren Med 2007;4:68-73.
50. Al-Alousi LM. Homicide by electrocution, Med Sci Law 1990;30:239-46.
51. Oehmichen M, Cropelin A. Temporal course of intravital and postmortem proliferation of epidermal cells after mechanical injury. An immu-nohistochemical study using bromodeoxyuridine in rats, Int J Legal Med 1995;107:257-62. American Society of Health-System Pharmacist, Bethesda 2009, pp.207-30.
54. Azzazy HM, Pelsers MM, Christenson RH. Unbound free fatty acids and heart-type fatty acid-binding protein: diagnostic assays and clinical applications. Clin Chem 2006;52:19-29.
60
55. Antman EM, Braunwald E. Acute Myocardial Infarction In: Braunwald E, Zipes D, Libby P (eds), Heart Disease. A textbook of Cardiovascular Medicine. WB Saunders Company, Philadelphia 2001, pp. 1131-5.
56. Bock JL. Evaluation of Cardiac Injury and Function. In: McPherson RA, Pincus MR (eds), Henry's Clinical Diagnosis and Management by Laboratory Methods (21th ed) Elsevier, China 2006, pp.219-30.
57. Adams JE, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury. Is MB Creatine Kinase the choice for the 1990s?. Circulation 1993;88:750-63.
58. Antman EM, Braunwald E. Acute myocardial infarction. In: Eugene Braunwald. Heart Disease A Textbook of Cardiovascular Medicine (5th ed), WB Saunders, Philadelphia 1997, pp.1186-8.
59. Dean KJ. Biochemistry and Molecular Biology of Troponin I and T. In Wu AHB (ed), Cardiac markers. Humana, Totowa 1998, pp. 193-204.
60. Korff S, Katus HA, Giannitsis E. Differential Diagnosis of Elevated syndromes. J Natl Med Assoc 2006;98(7):1067-70.
63. Nakataa T, Hashimoto A, Hase M, Tsuchihashi K, Shimamoto K. Human heart type fatty acid-binding protein as an early diagnostic and prognostic marker in acute coronary syndrome. Cardiology 2003;99:96-104.
64. Pelsers MM, Hermens WT, Glatz JF. Fatty acid-binding proteins as plasma markers of tissue injury. Clin Chim Acta 2005;352:15-35.
65. Akıncı S. Dobutamin stres ekokardiyografide iskemi varlığı ile stres sonrası serum kalp yağ asidi bağlayıcı protein düzeyi değişimi arasındaki ilişkisi.
Uzmanlık Tezi, Gazi Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, Ankara, 2007.
66. Colli A, Josa M, Pomar JL, Mestres CA, Gherli T. Heart Fatty Acid Binding Protein in the Diagnosis of Myocardial Infarction: Where Do We Stand Today? Cardiology 2007;108:4-10.
61
67. Glatz JFC, van der Putten RFM, Hermens WT. Fatty Acid Binding Protein as an Early Plasma Marker of Myocardial Ischemia and Risk Stratification. In:
WU Alan HB (ed), Cardiac Markers (2nd ed) Humana Press, Totowa New Jersey 2003, pp. 319-38.
68. Meng X, Ming M, Wang E. Heart fatty acid binding protein as a marker for postmortem detection of early myocardial damage. Forensic Sci Int 2006;160:11-16.
69. Ruzgar O, Bilge AK, Bugra Z, Umman S, Yilmaz E, Ozben B et al. The use of human heart-type fatty acid-binding protein as an early diagnostic biochemical marker of myocardial necrosis in patients with acute coronary syndrome, and its comparison with troponin-T and creatine kinase-myocardial band. Heart Vessels 2006;21:309-14.
70. Leibovici D, Shemer J, Shapira SC. Electrical injuries: current concepts.
Injury 1995;26:623-27.
71. Goodson ME. Electrically induced deaths involving water immersion. Am J Forensic Med Pathol 1993;14(4):330-3.
72. Schneider V. Electrocution in the bathtub. Arch Kriminol. 1985;176(3-4):89-95.
73. Lawrence RD, Spitz WU, Taff ML. Suicidal electrocution in a bathtub. Am J Forensic Med Pathol. 1985;6(3):276-8.
74. Silver MD. Cardiovascular Pathology(2nd ed), Churchill Livingstone, New York, 1996.
75. Özdemir Ç, Demirel B, Akar T, Odabaşı AB, Dinç AH. Elektrik akımı ile intihar: olgu sunumu. Gazi Tıp Dergisi 2007;18(2):89-91.
76. Şam B, Özdemir Ç, Çetin G, Üzün İ, Süner Ç. İstanbul’da 1990-2002 yılları arasında gerçekleşen elektrik akımıyla intihar olgularının değerlendirilmesi.
3. Anadolu Adli Bilimler Kongresi, poster sunumu, Eskişehir 2004.
77. Karger B, Süggeler O, Brinkmann B. Electrocution: autopsy study with emphasis on ‘‘electrical petechiae’’. Forensic Sci Int 2002;126: 210-13.
78. Marc B, Baudry F, Douceron H, Ghaith A, Wepierre JL, Garnier M. Suicide by electrocution with low-voltage current. J Forensic Sci. 2000;45(1):216-22.
79. Wright RK, Davis JH. The investigation of electrical deaths: a report of 220 fatalities J. Forensic Sci. 1980;25(3):514-21.
62
80. Risse M, Weiler G, Kaiser H. Rare suicidal death by electrocution using a timer and vital reaction. Arch Kriminol. 1996;197(5-6):149-54.
81. Fernando R, Liyanage S. Suicide by electrocution. Med Sci Law. 1990: 30(3);
219-20.
82. Anders S, Matschke J, Tsokos M. Internal current mark in a case of suicide by electrocution. Am J Forensic Med Pathol. 2001;22(4):370-3.
83. Şam B. Adli Tıp Atlası. Adli Tıp Kurumu Yayınları-7. İstanbul 2003: 141-51.
84. Fedakar R, Eren B, Akan O, Türkmen N, Saka E. Elektrik akımı ile intihar:
olgu sunumu. Adli Tıp Bülteni. 2004;9(3):87-90.
85. Bligh-Glover WZ, Miller FP, Balraj EK. Two Cases of Suicidal Electrocution Am J Forensic Med Pathol 2004; 25(3): 255-8.
86. Bailey B, Forget S, Gaudreault P. Prevalence of potential risk factors in victims of electrocution. Forensic Science Int. 2001;123(1):58-62.
87. Yamazaki M, Terada M, Ogura Y, Wakusugi C, Mitsukuni Y. A suicidal case of electrocution with hypnotic drug poisoning: an autopsy report. Nippon Hoigaku Zasshi 1997;51(2):95-101.
88. Anders S, Gehl A, Tsokos M. Suicidal electrocution using timers. Case reports and review of the literature. Arc Kriminol 2001;208(3-4):80-7.
89. Bonte W, Sprung R, Huckenbeck W. Problems in the evaluation of electrocution fatalities in the bathtub. Z Rechtsmed 1986;97(1):7-19.
90. Türkmen N, Eren B, Fedakar R, Durak D. Bursa ilinde elektrik akımı ile yaralanma sonucu ölümler. Ulus Travma Acil Cerrahi Dergisi 2008;14(1):65-9. concentrations as markers for myocardial infarction after coronary artery ligation in mice. Eur J Physiol 2000;439:416-22.
93. Fishbein MC, Wang T, Matijasevic M, Hong L, Apple FS. Myocardial tissue troponins T and I An immunohistochemical study in experimental models of myocardial ischemia. Cardiovasc Pathol 2003;12:65-71.
63
94. Fieguth A, Schumann G, Tröger HD, Kleemann WJ. The effect of lethal electrical shock on postmortem serum myoglobin concentrations. Forensic Sci Int. 1999;105(2):75-82.
95. Michiue T, Ishikawa T, Zhao D, Kamikodai Y, Zhu BL, Maeda H.
Pathological and biochemical analysis of the pathophysiology of fatal electrocution in five autopsy cases. Leg Med 2009;11: S549-52.
96. Wang Q, Michiue T, Ishikawa T, Zhu BL, Maeda H. Combined analyses of creatine kinase MB, cardiac troponin I and myoglobin in pericardial and cerebrospinal fluids to investigate myocardial and skeletal muscle injury in medicolegal autopsy cases. Leg Med 2011; Article in pres.
97. Guinard JP, Chiolero R, Buchser E, Delaloye-Bischof A, Payot M, Grbic A, et al. Myocardial injury after electrical burns: short and long term study.
Scand J Plast Reconstr Surg Hand Surg. 1987;21(3):301-2.
98. Hansen SH, Rossen K. Evaluation of cardiac troponin I immunoreaction in autopsy hearts: a possible marker of early myocardial infarction. Forensic Sci Int. 1999;99(3):189-96.
99. Glatz FC, Kleine AH, Van Nieuwenhoven FA, Hermens WT, Van Dieijen-Visser MP, Van der Vusse GJ. Fatty-acid binding protein as a plasma marker for the estimation of myocardial infarct size in humans. Br Heart J. 1994;
71:135-40.
64