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ADHESION MOLECULES

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(1)

BIO 480

ADHESION

MOLECULES

(2)

Bacterial Adherens Factors

• With the help of adhesion molecules,

microorganisms can attach to specific

receptors on the surface of the cells, colonize,

reach deeper and spread throughout the

body.

(3)

Adhesion factors

(4)

• Hemagglutinins

- molecules in the glycoprotein character - rather on the surface of viruses,

- helps in holding onto cells

- causes agglutination (hemagglutination) by binding to erythrocytes

(5)

• Fimbrial and afimbrial adhesins

- special adhesion proteins (adhesins, fimbrial adhesins) found at the distal ends of fimbriae (Type-I pilus)

(6)

• Fimbrial and afimbrial adhesins

- specific adhesion molecules (afimbrial adhesins) localized in the cell walls of bacteria

- interaction with specific receptors on the host cell surface

(7)

• Fimbria (piluses, microfibrils)

* in apatogenic or commensal enterobacteria

* Gram-negative microorganisms

(8)

• Type 1 Fimbria

• Type 2 Fimbria

• Type 3 Fimbria

• Type 4 Fimbria

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