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ADHESION MOLECULES

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(1)

BIO 480

ADHESION

MOLECULES

(2)

MUCIN-LIKE ADHESION MOLECULES

(3)

• GlyCAM-1

• CD34

• P-selecting glycoprotein ligand-1 (PSGL-1)

(4)

CADHERIN-GROUP ADHESION

MOLECULES

(5)

Cadherins are involved in calcium- dependent cell-cell adhesion.

The molecule of a Cadherin binds to the molecule of similar Cadherins on

the neighboring cell.

(6)

Cadherins

1. Epithelial cadherines

(E-cadherines or uvomorulin, LCAM)

2. Neural cadherines (N-cadherines or A-CAM) 3. Placental cadherines (P cadherines)

4. Vascular cadherines (V- cadherines)

(7)

UNCLASSIFIED ADHESION MOLECULES

(8)

• CD44:

• (Extracellular matrix receptor III, Hermes)

• a membrane glycoprotein

• CD36

• Platelet glycoprotein VI, GPIIIb

• plays a role in cell phagocytosis leading to apoptosis

(9)

• Laminine

• Molecular structure of the basement membrane

• Embryogenesis, development and remodeling of tissues

• Fibronectin

Embryogenesis, angiogenesis, hemostasis,

thrombosis, inflammation and wound healing

(10)

Soluble (Soluble) Cell Adhesion Molecules

• ICAM-1

• sVCAM-1

• sE-selectin

• sp-selectin

Referanslar

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