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CELL RECEPTORS

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BIO 473

CELL RECEPTORS

6. WEEK

(2)

Major classes of surface (MEMBRAN) receptors for

signaling

Ligand Ion channel-linked receptors

(3)

Translate a chemical signal into an electric signal

Activate cells

Medicines and neurotoxins affect

ion channels

(4)

Acetylcholine receptor/channel

Action potentials

Open voltage gated

Ca channels

(5)

Acetylcholine receptor/channel

Ca diffusion into the cell

Synaptic vesicles release

acetylcholine

(6)

Acetylcholine receptor/channel

Diffusion of acetylcholine across synaptic clef

Acetylcholine binds

receptor

(7)

Acetylcholine receptor/channel

Na channels opens

Depolarization

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Acetylcholine receptor/channel

Depolarization: threshold…

Action potential

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