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Veterinary Medicine

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Academic year: 2021

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General Information

• According to toxins and toxidrome classes

• Ibotenic acid/Muscimol • Cyclopeptide • Muscarine • Hallucinogens • Monomethyl hydrazine • GI Irritants

• Acute renal failure

• Amanita sp. – most deaths in dogs (for mushroom poisoning) • Can affect multiple organ at the same time

• Early diagnosis is important

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Liver toxic mushrooms

• Amanita phalloides (Death Cap Mushroom) • Amanita ocreata (Angel of Death)

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Hallucinogenic Mushrooms

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• Toadstool Mushrooms

• - Amanita pantherina (Panther Cap) • - Amanita muscaria (Fly Agaric)

• Mushrooms Containing Muscarinic Agents • - Inocybe

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• Mushrooms Containing

Muscarinic Agents

• - Inocybe • - Clitocybe •

• False Morel Mushrooms

• - Gyromitra esculenta (Beefsteak) • - Gyromitra caroliniana

• - Mushrooms in the Verpa genre

• - Mushrooms in the Helvella genre

• Mushrooms That Cause

Gastrointestinal Distress

• - Boletus

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Classification

• contain diverse secondary metabolites (cyclopeptides,

monomethylhydrazine, orelline/orellanin, muscarine, ibotenic acid and muscimol, psilocybin, and unknowns) that on

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• Depending on the type of mushroom, the quantity eaten, the time elapsed since eaten, and several other factors, the signs of toxicity will vary. But common signs might include any of the following: • Vomiting • Diarrhea • Abdominal pain • Weakness • Lethargy

• Yellowing of the skin (jaundice) • Uncoordinated movements • Excessive drooling (ptyalism) • Seizures

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Diagnosis

• Anamnesis (onset and nature of the symptoms)

• Complete blood count, biochemistry profile, and urinalysis

--• abnormally low blood glucose levels (hypoglycemia)

• abnormally high levels of liver enzymes due to liver damage • sample from the stomach to identify the type of mushroom.

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• Inexperience in harvesting wild mushrooms • Owner substance abuse

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Treatment

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Treatment cont’ed

Cyclopeptide

• IV glucose or dextrose • Fresh frozen plasma • Blood transfusion • Vitamin K • Potassium (hypokalemia) • Furosemide • Dopamine MMH • Diazepam • Muscarine • Atropine Ibotenic acid/Muscimol • Diazepam Hallucinogens • Diazepam

Acute renal failure

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• Check North American Mycological Association

• https://namyco.org/

• Turkey- Mushroom Flora

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