• Sonuç bulunamadı

Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats.

N/A
N/A
Protected

Academic year: 2021

Share "Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats."

Copied!
1
0
0

Yükleniyor.... (view fulltext now)

Tam metin

(1)

Antihypertensive effects of Undaria pinnatifida

(wakame) peptide on blood pressure in spontaneously

hypertensive rats.

Kunio Suetsunaa, Keisei Maekawab and Jiun-Rong ChenSuetsuna K;Maekawa

K;Chen JR

Abstract

We examined the angiotensin I-converting enzyme (ACE) inhibitory activity and antihypertensive effect of the hot water extract of wakame, Undaria pinnatifida. Ten dipeptides were isolated from the extract by several steps of chromatography, and their amino acid sequences were Tyr-His, Lys-Trp, Lys-Tyr, Lys-Phe, Phe-Tyr, Val-Trp, Val-Phe, Ile-Tyr, Ile-Trp, and Val-Tyr. Both single administration and repeated oral administration of synthetic Tyr-His, Lys-Tyr, Phe-Tyr, and Ile-Tyr significantly decreased blood pressure in spontaneously hypertensive rats.

Referanslar

Benzer Belgeler

‐  Trp  ‐  His  ‐  Lys  ‐  His  ‐  Glu  ‐  Leu  ‐  His  ‐  Arg  ‐  Lys  – COOH)  peptid  epitopunun  mikrodalga  destekli  katı  fazda  peptid 

Bununla beraber onların - bü­ tün anlayışsızlıklarına rağmen, ileri geri sözler söylemekte ıs­ rar ettikleri yetmiyormuş gibi - on parmaklarında on

Effect of the Methanol Extract of the Solid-State Culture of Chang-Chih (MS-SSC-CC) on the Changes in Systolic Blood Pressure (A) and Diastolic Blood Pressure (B) of

MS extract of the SSC type was able to effectively lower the systolic blood pressure (SBP) and diastolic blood pressure (DBP) of SHR, but not of WKY rats, the results

Intravenous administration of DC-015 and prazosin (both at 0.01, 0.05 and 0.1 mg/kg) induced a dose-dependent reduction of mean arterial pressure (MAP) which reached a maximal

Injection of PTB-6 into the intracerebral ventricles of SHRs lowered the systolic arterial blood pressure and heart rate. The berberine derivative PTB-6 is an effective

Both single administration and repeated oral administration of synthetic Tyr-His, Lys-Tyr, Phe-Tyr, and Ile-Tyr significantly decreased blood pressure in spontaneously

[r]