BIO 440
MICROBIAL
BIOTECHNOLOGY
Product produced by microorganisms with industrial scale:
• Vitamins: B12, Riboflavin
• Steroids: Production of cortisone from
Rhizopus nigricans
Product produced by microorganisms with industrial scale:
• Amino acids used in the food industry: L- Glutamate (monosodium glutamate, Glycine, L-Cysteine, L-Tryptophan + L-Histidine, Aspartame (L-phenylalanine + L-aspartic Acid), L-Lysine, DL-Methionine
• Example: Industrial lysine production using
Corynebacterium glutanicum
Product produced by microorganisms with industrial scale:
• Example: Industrial lysine production using
Corynebacterium glutanicum
Industrially produced microbial enzymes
• Amylase (starch-degradation)
• protease
• Invertase (sucrose-destruction)
• Glucose oxidase
• Glucose isomerase
Industrially produced microbial enzymes
• pectinase
• Renner
• cellulases
• lipase
• lactase
• DNA polymerase
Examples of enzymes that function under extreme environmental conditions
•Acid-resistant avizyme to digest the fibrous portion of the feed in the stomach of poultry
Examples of enzymes that function under extreme environmental conditions
•Heat-resistant Pyrococcus woesei amylase in starch digestion
•Enzyme immobilization procedures
