藥學科技上課心得：林松逸

(1)

Scifinder 使用心得報告

首先登入之後，打入要查的主題，這次選定的是_{Gefitinib,其中包含此藥名的 paper}

有_{6547 筆}

太多筆，於是逐步增加關鍵字，例如，我想查的是其在臨床應用，將其語言限制勾選 English，文件類型勾選 clinical trial,剩下 328 筆，

(2)

若我想要的是其肺癌上之應用，便在其關鍵字上加lung cancer，剩下 139 筆，並選擇我想要的paper

(3)

(4)

THOMOSON Innovation 使用心得報告

(5)

Abstract

The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the

treatment of proliferative conditions mediated by CXCR4 receptors or for the treatment of viral infections. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis, or for reducing entry of HIV in to a cell while not reducing the capacity of the stem cells to proliferate. The compounds may be useful for long term treatment regimes.

(6)

First Claim

1. A compound selected from the group consisting of:

• pharmaceutically acceptable salt or ester.

Assignee / Applicant

Original: Emory University, Atlanta, GA, US Inventor

Liotta Dennis C., Atlanta, GA, US Snyder James P., Atlanta, GA, US Zhan Weiqiang, Decatur, GA, US Publication Number / Date

/ 2011-12-20

US8080659B2

Application Number / Date

/ 2007-07-11

US2007776476A

Priority Number / Date

US2007776476A

/ 2007-07-11

IPC

Current IPC Invention Version Additional Version

Full C07D 403/12 C07D 403/14 A61K 31/506 A61P 35/00 20060101 20060101 20060101 20060101 - - Main Group - - - - Subclass - - - -

Original IPC Invention Version Additional Version Advanced/Full C07D 403/1220060101 - -

(7)

C07D 403/14 A61K 31/506 A61P 35/00 20060101 20060101 20060101 Core/Main Group - - - - Subclass - - - -

SciFinder Scholar 資料庫主要包含 CA Plus 與 MEDLINE 等資料庫，提供超過 3,000 萬筆的文獻摘要，來自於31 個世界專利組織中超過 350 萬筆的專利資料，且大部分有免費的全文可供研究者瀏覽。此外尚有會議論文、技術報告、圖書、學位論文、綜評、會議摘要、電子期刊、網路預出刊等資料，每日更新。主題範疇涵蓋所有化學化工領域，包括農業科學、生物與生命科學、工程與應用化學、食品科學、普通化學、地質科學、材料科學、醫藥科學、物理學、聚合物科學等。著實令人激賞!! THOMSON Innovation 同時檢索專利情報、市場訊息、商情新聞、科技文獻資訊,快速尋找專利情報，線上直接調閱專利原文或訂閱File Histories,專家提供專利重新改寫服務，迅速了解專利重點內容，節省閱讀寶貴時間，令人為之一振!!