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Pharmacology 1 and

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(1)

Seda%ve, hypno%c, neurolep%c/an%epilep%c,

an%seizure drugs, analep%cs, prescrip%on samples, pharmaceu%cal procedures

Refer lecturer for course updated notes.

Students are oblidged to follow the courses for evalua%on process and presented notes are preliminary dra>s for the whole evalua%on

process.

Pharmacology 1 and

Prescription Knowledge

(2)

•  Seda%ve and hypno%c drugs

•  Introduc%on

•  General pharmakokine%c proper%es

•  General pharmacodynamic proper%es

•  Clinical Uses

•  Adverse Effects

•  Problem-Oriented Pa%ent example

(3)

Benzodiazepines

Agents with full agonist ac%vity at benzodiazepine site

•  (Alprazolam, Chlordiazepoxide , Clorazepate ,

Clonazepam ,Diazepam ,Estazolam ,Flunitrazepam ,Flurazepam ,Lorazepam ,Midazolam ,Oxazepam ,Temazepam ,Triazolam

Nonbenzodiazepines ac%ve mainly at the type 1 benzodiazepine site

•  eszopiclone, zaleplon, and zolpidem

•  Mechanism of ac%on

•  Dose-Response

(4)

•  Barbiturates

•  Amobarbital, aprobarbital, butabarbital, barbital, mephobarbital,

methohexital, pentobarbital, phenobarbital, primidone, secobarbital, thiopental

•  Mechanism of ac%on

•  Dose-Response

(5)

•  Chloral hydrate

•  Erhchlorvynol

•  Etomidate

•  Glutethimide

•  Methprylon

•  Meprobamate

•  Methaqualone

•  Paraldehyde

•  Propofol

•  Ramelteon

•  Dexmedetomidine

(6)

•  Tolerance/Withdrawal

(7)

•  Ramelteon/Melatonin

(8)

antiepileptic/antiseizure/antipsycotic

•  Epilepsy

•  Seizures

•  Post-ictal

•  Grand mal seizure

•  Pe%t mal seizure

•  Myoclonus

(9)

•  Mechanism of ac%on

•  Sodium channel blockers

•  GABA receptor agonists

•  GABA reuptake inhibitors

•  GABA transaminase inhibitors

•  AEDs with poten%al GABA mechanism of ac%on

•  Glutamate blockers

•  AEDs with other mechanism of ac%ons

•  Neuronal potassium channel openers

(10)

Psychotropic Drugs

Behaviour Modification Medications in Veterinary Medicine

•  Augmenta%on of Behaviour Modifica%on

•  Reduc%on of Stress

•  Seda%on

•  Dura%on of Therapy

•  Informed Consent

•  An%deppresants

•  Benzodiazepines and trazodone

•  Buspirone

•  Combina%on therapy

•  Client expecta%ons – Proxy situa%ons

•  Case examples

Referanslar

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