Pharmacology 1 and

(1)

Analgesic Drugs

Refer lecturer for course updated notes.

Students are oblidged to follow the courses for evalua:on process and presented notes are preliminary dra=s for the whole evalua:on

process.

Pharmacology 1 and

Prescription Knowledge

(2)

•  Types of pain

•  Deﬁni:on of analgesia

•  Central analgesics

(3)

Narco:cs

•  Opioids (morphine&morphine like drugs)

•  Natural

•  Semi synthe:c

•  Synthe:c

•  Endogeneous opiates

(4)

•  Non-narco:cs

•  NSAID

•  Aspirin

•  Paracetamol

•  Diclofenac

•  Piroxicam

•  Ibuproﬁn

•  Ketoproﬁn

(5)

•  Inﬂamma:on process

•  Eﬀects of Eukanazoids in inﬂamma:on

(6)

•  Mechanism of ac:on of NSAID

•  Clinical eﬀects of NSAIDs (analgesia, an:inﬂammatory, an:pyre:c)

(7)

Classiﬁca:on of NSAIDs

•  COX-1 selec:ve inhibitors

•  Nonselec:ve cox inhibitors

•  More Cox-2 selec:ve inhibitors

•  Cox-2 selec:ve inhibitors

(8)

•  Analgesic drugs

•  Use and clinical applica:ons

•  Side/Adverse eﬀects

(9)

•  Renal eﬀects

•  Cardiovascular eﬀects

•  Eﬀects on platelets

(10)

•  Opioids

•  Mechanism of Ac:on

•  Physical Dependence and Addic:on

(11)

•  Drugs of neuropathic pain

•  Amitriptyline

•  Carbamezepine

•  Sodium valproate

•  Gabapen:noids