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Şimdi indir ( 9 sayfa )

Tam metin

(1)

Mutations

Mutations

(2)

Gene Mutations

• Change in the nucleotide

sequence of a gene

• May only involve a single nucleotide

• May be due to

copying errors,

chemicals, viruses, etc.

(3)

Types of Gene Mutations

• Include:

• Point Mutations

• Substitutions

• Insertions

• Deletions

• Frameshif

(4)

Point Mutation

• Change of a single nucleotide

• Includes the

deletion, insertion, or substitution of

ONE nucleotide in a gene

(5)

Point Mutation

• Sickle Cell

disease is the result of one

nucleotide substitution

• Occurs in the hemoglobin gene

(6)

Frameshift Mutation

• Inserting or

deleting one or more nucleotides

• Changes the

“reading frame” like changing a sentence

• Proteins built incorrectly

(7)

Frameshift Mutation

• Original:

• The fat cat ate the wee rat.

• Frame Shif (“a” added):

• The fat caa tet hew eer at.

(8)

Amino Acid Sequence Changed

(9)

Gene Mutation Animation

Referanslar

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