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In silico analysis of mutant p53(R249S) oncogenicity in hepatocellular carcinoma

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Figure 1.1: Diagrammatic illustration of the history of p53 functions since its discovery in 1979
Figure 1.2: High frequency of missense mutations affecting p53 compared to other tumor suppressors
Figure 1.3: p53: a two-faced cancer gene. (Kastan MB and Berkovich E, 2007) [14]
Figure 1.4: Distribution of p53 mutations. (Weinberg RA, 2006) [11]
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