5.1 Sonuçlar
Sonuç olarak yapılan bu çalışmada değişik fonksiyonel gruplar taşıyan kinazolinon türevleri sentezlendi.
Sentezlenen bileşiklerin karakterizasyonu FT-IR, NMR, elementel analiz ve diğer metodlarla yapıldı.
Sentezlenen bileşiklerin bazı gram pozitif ve gram negatif bakterilere karşı antimikrobiyal aktiviteleri incelendi.
Sentezlenen bileşiklerden özellikle 8 numaralı bileşiğin diğer kinazolinon türevlerine göre daha etkili olduğu tespit edildi.
5.2 Öneriler
Sonuç olarak bu çalışmada sentezlenen bileşiklerden bazılarının antimikrobiyal özellik göstermesi bu bileşiklerin farmakolojik araştırmalarda kullanılabileceği yönündeki çalışmalara ışık tutacaktır.
Kinazolinon temel bileşiği benzen ve pirimidin halkalarından meydana gelmiştir. DNA‘nın pirimidin bazlarına benzerliğinden dolayı kinazolinon türevleri çağımızın hastalığı olan kanser tedavisinde ilaç etken maddesi olarak kullanı labilirliği yönünde yapılacak bilimsel çalışmalara katkıda bulunacaktır.
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http://www.yogunbakimdergisi.org/managete/fu_folder/2003-02/html/2003-3-2-118- 128
EKLER
ÖZGEÇMĠġ
KĠġĠSEL BĠLGĠLER
Adı Soyadı : Ural Ufuk DEMİREL
Uyruğu : T.C
Doğum Yeri ve Tarihi : Ankara 07.01.1984
Telefon : 5347287152
Faks :
e-mail : uralufukdemirel@hotmail.com
EĞĠTĠM
Derece Adı, Ġlçe, Ġl Bitirme Yılı
Lise : Karatay Anadolu Lisesi 2002
Üniversite : Selçuk Üniversitesi Fen Fakültesi Kimya Bölümü 2009 Yüksek Lisans : Selçuk Üniversitesi Fen Bilimleri Enstitüsü (devam) Doktora :
YABANCI DĠLLER
İngilizce
YAYINLAR
Demirel, U.U., Erdem, S., Arslan, G., Yilmaz, A., "Kaliks[4]arenin"Upper Rim"
Üzerinden Schiff Baz Türevlerinin Sentezi, Karakterizasyonu ve Dikromat Anyon Ekstraksiyonunda Kullanılması", 25. Ulusal Kimya Kongresi" poster sunum, OP-364, Erzurum, 2011.
Kırdı, İ., Arslan, G., Demirel, U.U., Yilmaz, A., "Kaliks[4]arenin Schiff Baz Türevi ile Membran Hazırlama", 6. Ulusal Analitik Kimya Kongresi, sözlü sunum, 11, 03-07 Eylül 2012, Mustafa Kemal Üniversitesi, Hatay.