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CANCER CELL

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Academic year: 2021

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(1)

BIO 478

CANCER CELL

(2)

The factors that lead to cancer formation

(3)

• Environmental factors and geographical

• Distribution

• Age

• Genetic

• Chemicals

• Radiation

• Precancerous diseases

• Viral carcinogens

(4)

Chemical Carcinogens

• They are different in structure and contain both natural and synthetic products.

• Some have direct carcinogenic effects, while others have indirect effects.

(5)

Indirect Effects Agents (Procarcinogens)

• Polycyclic and heterocyclic hydrocarbons

• Aromatic amines and azo dyes

• Natural herbal and microbial products

• Nitrosamine and nitrites

• Insecticides

• Fungucide

(6)

Radiation

• Radiation-containing rays such as solar

ultraviolet ray, X-ray, nuclear fusion cause many malignancies, especially leukemia.

(7)

• mutations

• protoonkogen activation

• tumor suppressor gene inhibition

• formation of thymine dimers in DNA

(8)

Precancerous Diseases

• Leukoplakia

• Cirrhosis

• Endometrial hyperplasia

• Chronic gastritis

• Fibrocystic disease

Referanslar

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