Reproductive Endocrinology
Melatonin
• Melatonin is a hormone secreted by the pineal (epiphysis) gland located at the back of hypothalamus.
• It displays its effect by starting and ending the sexually active season in poliestric animals (sheep, goat, horse).
• The impulses regarding light in the eyes are transformed into neurological impulses in the retina and these neurological impulses travel to the suprachiasmatic nucleus located in front of hypothalamus which determines the secretion rhythm of the pineal gland directly by retino- hypothalamic pathway.
Reproductive Endocrinology
Melatonin
• Signals emenating from the suprachiasmatic nucleus are transferred through the preganglionic and postganglionic fibers to the pineolocytes which are the main cells of the pineal gland.
• The pineal gland changes the melatonin secretion levels in accordance with duration of daylight depending on the neural information coming from the eyes.
• Darkness increases the sympathic neural activity on the pineal gland, thus increasing melatonin secretion rate.