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Chromosome mapping and segregation of genes linked on the same chromosome

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Chromosome mapping and segregation of

genes linked on the same chromosome

Prof. Dr. İsmail AKYOL Prof. Dr. M. Ali YILDIZ Prof. Dr. M. Muhip ÖZKAN

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Outline of course

• Chromosomes in eukaryotes contain large numbers of genes, whose locations are fixed along the length of the chromosomes.

• Unless separated by crossing over, alleles on the same chromosome segregate as a unit during gamete formation.

• Crossing over between homologs during meiosis creates recombinant gametes with different combinations of alleles that enhance genetic variation.

• Crossing over between homologs serves as the basis for the

construction of chromosome maps. The greater the distance between two genes on a chromosome, the higher the frequency of crossing

over is between them.

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