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精白米及不同量米麩對大白鼠體內膽固醇代謝的影 響

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精白米及不同量米麩對大白鼠體內膽固醇代謝的影 響

本實驗目的在於探討台農 67 號稻米之精白米及不同量米麩纖維對大老鼠 (Wistar 品系 ) 膽固醇代謝的影響。雄性大白鼠約 280g ,隨機分為八組,再分兩大組供實驗Ⅰ及Ⅱ

。實驗Ⅰ:以玉米澱粉為醣類來源是玉米澱粉組、精白米取代玉米澱粉為精白米組,

各添加 1% 膽固醇的玉米澱粉加膽固醇組及精白米加膽固醇組。實驗Ⅱ:精白米加膽固 醇組其纖維來源為米麩,依含量分為 2% 米麩組、 5% 米麩組、 10% 米麩組及 20% 米 麩組。實驗Ⅰ及Ⅱ皆進行四週後取下腔動脈血、肝臟,並收集最後一週的糞便,以供分析 血清膽固醇、三酸甘油酯及總脂質,肝臟總膽固醇和總脂質,糞便中酸性及中性固醇

。結果發現飼料中含 1% 膽固醇會促肝臟總膽固醇及總脂質增加,並增加糞便總中性固 醇及酸性固醇排出。而精白米比玉米澱粉有較低的血清總膽固醇,及促進糞便中總膽 酸排出,但不會增高糞便中總膽酸排出濃度。而米麩添加量會增加糞便總膽酸排出,

且也能稀釋總膽酸排出濃度。因此由實驗結果顯示,精白米可以有效減少血清總膽固 醇及增加總膽酸的排出,有利於體內膽固醇的排除,米麩則可以抑制營養素的吸收消 化及增加總膽酸的排出,但對體內膽固醇的影響並不明顯。

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