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Development of a non-radioactive diagnostic test for the detection of microsatellite instability in colorectal cancer

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Academic year: 2021

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Figure  1.  Illustration  o f the  action  o f the  E.  coli Mut HLS mismatch  repair system  on  a  mispair at  a  replication fork.
Figure IM o d e l fo r m ism atch recognition in S.  cereviseae.  The various postulated complexes  between  MSH2  and  cither  MSH3  or  MSH6  are  illustrated  interacting  with  either  a  single-base  substitution  mispair or an  insertion/ deletion  m
Figure  3.  D escription  o f the  extent  o f clinical  heterogeneity  in  hereditary  colorectal  cancers:  1
Figure 5.  Visualisation  o f  the PCR  amplification products  o f  six microsatellite  loci  on  2%  Agarose-gel
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