走路方案對急性骨髓性白血病病患接受化學 治療期間疲憊改善之效果

走路方案對急性骨髓性白血病病患接受化學 治療期間疲憊改善之效果

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，控制組病患的距離減少 26% ； (2) 實驗組病患的疲憊程度、疲憊干擾 日常生活程度、症狀困擾及情緒障礙之改善效果皆較控制組佳。

本研究結果由於樣本數少，以致實驗組與控制組之差異未能呈現統計上 之顯著意義。但與多數運動研究結果一致，亦即活動 / 運動在癌症治療 期間的好處是不可磨滅的。因此，在臨床照護中，於此類住院病患接受 化學治療期間，執行適當的走路活動可有助於降低疲憊。

Effects of walking program on decreasing fatigue i n acute myelogenous leukemia patients receiving

chemotherapy

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The purpose of this pilot study is to examine the effects of walking program on reducing fatigue in acute m yelogenous leukemia (AML) patients receiving chemotherapy. We used a longitudinal repeated-measure q uasi-experimental research design for this study. The eligible subjects were AML patients who received ch emotherapy. Patients were recruited using convenient sampling from a medical center in Middle Taiwan. P atients in the training group (n=7) had a 10-minute walk daily for 5 days a week (including test day) after c hemotherapy. The training program continued for 3 weeks. The heart rate during training was controlled be low the resting heart rate per minute plus 30 (HRresting + 30). 8 patients were in the control group. All pati ents were interviewed four times: on the first day of chemotherapy (before treatment), and on the 7th, 14th, and 21st day after chemotherapy. We used the following instruments to measure the variables: 12-min wal king test, Brief Fatigue Inventory (BFI), Symptom Distress Scale- Chinese Modified Form (SDS-CMF), Pr ofile of Mood States (POMS)- Anxiety and Depression subscales, and vital signs measurement.

Data were analyzed using descriptive analyses, Chi-square test, t test, Shapiro-Wilk normality test, and two / one factor repeated measure ANOVA. The distance of 12-min walk increased 35% in the training group, and decreased 26% in the control group. The improving effects of the training group is better than that of t he control group on the degree of fatigue, the degree of ADL interference of fatigue, symptom distress, and mood disturbance.

Even though our data did not show a significant difference between the training and control groups due to t

he small sample size, we did find an agreement with most current exercise interventions studies supporting

the benefits of activity/exercise during cancer treatment. In conclusions, proper walking activity may help t

o reduce fatigue while the cancer inpatients during chemotherapy.