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Response to: Comment on "the effects of hemodialysis on tear osmolarity"

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Letter to the Editor

Response to: Comment on

(The Effects of Hemodialysis on

Tear Osmolarity

)

Muhittin Taskapili,

1

Kubra Serefoglu Cabuk,

2

Rukiye Aydin,

3

Kursat Atalay,

2

Ahmet Kirgiz,

2

Dede Sit,

4

and Hasan Kayabasi

4

1Prof. Dr. N. Resat Belger Beyoglu Eye Training and Research Hospital, 34421 Istanbul, Turkey 2Bagcilar Training and Research Hospital, Ophthalmology Department, 34200 Istanbul, Turkey 3Ophthalmology Department, Medipol University, 34214 Istanbul, Turkey

4Bagcilar Training and Research Hospital, Nephrology Department, 34200 Istanbul, Turkey

Correspondence should be addressed to Kubra Serefoglu Cabuk; [email protected] Received 25 April 2016; Accepted 23 June 2016

Academic Editor: Biju B. Thomas

Copyright © 2016 Muhittin Taskapili et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

We thank Onder Ayyildiz and Gokhan Ozge for their interest and comment on our paper “The Effects of Hemodialysis on Tear Osmolarity” [1, 2]. They thought that detection of TO would be performed at the same time of the day regarding the duration of hemodialysis (HD) which may avoid the bias of the methodology according to the study of Niimi et al. [3]. Niimi et al. have enrolled 38 medically healthy neophytes. Their subjects reported to the CRC an average of14±2.0 hours (7–17 hours) after awakening for baseline measurements and sleeping at the CRC, thereby allowing for uniform environmental exposure (e.g., humidity and temperature) and timely collection of measurements upon awakening.

The physical conditions of our clinic are not suitable for all HD patients to report 7 hours after awakening for baseline measurements and sleeping one day thereby allow-ing for uniform environmental exposure (e.g., humidity and temperature) and timely collection of measurements upon awakening.

In our Hemodialysis Unit, two HD sessions have been performed; the first session was between 8:30 and 12:30 and the second session was between 13:00 and 17:00. 23 patients were in the first session and 20 patients were in the second session in our study. Tear osmolarity (TO) measurements have been performed one minute before the beginning of HD

Table 1: Pre-HD and post-HD tear osmolarity according to HD sessions.

First session Second session 𝑝 Pre-HD tear osmolarity 312.2± 16.6 315.6± 18.9 0.528 Post-HD tear osmolarity 301.6± 18.3 302.1± 12.3 0.929

Statistical method: Student’s𝑡-test independent.

and 30 minutes after the termination of HD. There was no statistically significant difference between pre-HD tear TO measurements and between post-HD TO measurements of these two sessions (Table 1).

Competing Interests

None of the authors of this paper has a financial or personal relationship with other people or organisations that could inappropriately influence or bias the results.

References

[1] O. Ayyildiz and G. Ozge, “Comment on ‘the effects of hemodial-ysis on tear osmolarity’,” Journal of Ophthalmology, vol. 2016, Article ID 6890685, 1 page, 2016.

Hindawi Publishing Corporation Journal of Ophthalmology

Volume 2016, Article ID 1925683, 2 pages http://dx.doi.org/10.1155/2016/1925683

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2 Journal of Ophthalmology

[2] M. Taskapili, K. Serefoglu Cabuk, R. Aydin et al., “The effects of hemodialysis on tear osmolarity,” Journal of Ophthalmology, vol. 2015, Article ID 170361, 5 pages, 2015.

[3] J. Niimi, B. Tan, J. Chang et al., “Diurnal pattern of tear osmo-larity and its relationship to corneal thickness and deswelling,”

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Şekil

Table 1: Pre-HD and post-HD tear osmolarity according to HD sessions.

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