The Fifth Conference “ Nuclear Science and Its Application”, 14-17 October 2008
COMPLEXATION OF THORIUMflV) WITH GUANINE AT VARIABLE
TEMPERATURES
S.TEKSÖZ. C. ACAR. P.ÜNAK
Department o f Nuclear Applications, Institute of Nuclear Sciences, Ege University, 35100 Bornova l2mir, Turkey
In current study, it was aimed to investigate proton-ligand stability constants of guanine, a purine base o f DNA, and its metal-ligand stability constants formed with Th(TV). The m etal complexes o f the purine and pyrimidine bases play a dominant role in biochemical systems. Also, the behaviors o f actinides are very important in nuclear waste.
For this purpose, experiments were performed by potentiometric titration according to obtained experimental conditions that were designed by the help of the HySS program. The potentiometric results were transferred to HYPERQUAD2006 computer program and stability constants were
Section IV. Application O f Nuclear Technologies In Industry, Medicine And Agriculture
The Fifth Conference “ Nuclear Science and Its Application”, 14-17 October 2' computed for relevant metal ions.
The ionic strength was adjusted to 0 .1M with Potassium chloride (KC1). All o f the titrations were carried out with carbonate-free 0.1M sodium hydroxide (NaOH) using Metrohm-665 Dosimat and 686 Titroprocessor automatically using MET program. Potentiometric calibration was done using GLEE computer program according to run Gran method.
It is important to have knowledge about protonation and complexation constants to be able to understand what happens in a complex formation systems. Monomeric and polymeric species were found for Th(TV) at 25°C, 37 °C and 45 °C. In conclusion, it is indicated that formation o f complex changes the value of stability constants at variable temperatures.
Section IV. Application O f Nuclear Technologies In Industry, Medicine And Agriculture
