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What if the silent disease comes with the reality? Comment on: Prevalence of bone mineral density testing and osteoporosis management following low-and high-energy fractures

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What if the silent disease comes with the reality?

Comment on: Prevalence of bone mineral density

testing and osteoporosis management following

low-and high-energy fractures

LETTER TO THE EDITOR

Acta Orthop Traumatol Turc 2015;49(2):224 doi: 10.3944/AOTT.2015.14.0001

To the Editor,

We read with interest the article entitled “Prevalence of bone mineral density testing and osteoporosis man-agement following low- and high-energy fractures” by Angthong et al. in Vol. 47, No 5 (2013) of your journal.

[1] We congratulate them for their inspiring work.

How-ever, the study itself has some methodological draw-backs, and contains false interpretations of results that lead to misunderstanding:

1. Inclusion of both low- and high-energy fracture patients to test probability of DEXA examination ren-ders the criteria inconsistent. In the literature, the inci-dence of osteoporosis is much less likely in high-energy fractures.[2-4] Thus, DEXA testing probability by the

orthopedic surgeons is very low. In addition, the study’s high-energy fracture group comprised only six patients, which also limits its power.

2. The authors covered all low-energy fractures in the study, including ankle, calcaneus, proximal humerus, and tibial plato, all of which might have been complicated by other pathologies and secondary causes of osteoporosis.

[4,5] While deciding which patients are to be tested,

litera-ture-based guidelines should be used. Had patients with only hip or vertebral low-energy fractures been selected, the results would be better understood.

3. Another issue that attracted our attention is that all post-menopausal women, and men aged 50 and older, should be evaluated clinically for risk of osteoporosis in order to determine the need for BMD testing. However, DEXA scanning is not a prerequisite for initiating os-teoporosis treatment in patients who sustain low-energy fractures in either their vertebra or hip, since a clinical diagnosis can often be made in at-risk individuals. BMD testing is recommended only to determine severity of the disease, and to assess the response or efficacy of an ap-proved osteoporosis drug therapy for these patients.[4,5]

Osteoporosis is a silent disease until complicated

by low-energy fractures.[5] We entirely agree with the

authors’ statement that many patients are not receiving adequate information about prevention or appropriate testing to diagnose osteoporosis or osteoporosis risk.

Harun Reşit GÜNGÖR Nusret ÖK

Pamukkale University Faculty of Medicine, Department of Orthopedics and Traumatology, Denizli, Turkey

e-mail: hrgungor@gmail.com

References

1. Angthong C, Rodjanawijitkul S, Samart S, Angthong W. Prevalence of bone mineral density testing and osteoporo-sis management following low- and high-energy fractures. Acta Orthop Traumatol Turc 2013;47:318–22. CrossRef

2. Kanis JA on behalf of the World Health Organization Scientific Group. Assessment of Osteoporosis at the Pri-mary Health Care Level. 2008 Technical Report. Univer-sity of Sheffield, UK: WHO Collaborating Center; 2008. 3. Tosteson AN, Melton LJ 3rd, Dawson-Hughes B, Baim S, Favus MJ, Khosla S, et al. Cost-effective osteoporosis treatment thresholds: the United States perspective. Os-teoporos Int 2008;19:437–47. CrossRef

4. Dawson-Hughes B, Tosteson AN, Melton LJ 3rd, Baim S, Favus MJ, Khosla S, et al. Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA. Osteoporos Int 2008;19:449–58. CrossRef

5. National Osteoporosis Foundation. Clinician’s Guide to Prevention and Treatment of osteoporosis. Washington, DC: National Osteoporosis Foundation; 2013.

Available online at www.aott.org.tr doi: 10.3944/AOTT.2015.14.0001 QR (Quick Response) Code

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