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Toxicity assessment of Hypericum olympicum subsp. olympicum L. on human lymphocytes and breast cancer cell lines

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Academic year: 2021

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Table 1. The results of chromatographic analysis of Hypericum  olympicum subsp. olympicum
Table 1 (Continued) Compound a RI b % Area cFlower Trunk Undecane 1100 0.12 1.47 Phenylethyl Alcohol 1106 0.10 0.04 Maltol 1106 0.07 0.14 2(3H)-Furanone, dihydro-5-propyl- 1130 0.21 0.29 2(3H)-Furanone,  ethyl-4-hydroxymethyl- 1139 0.20 0.27 Furaneol 1139
Table 2. Results of Micronuclei (MN) and Sister Chromatid Exchange (SCE) assays in cultured human lymphocytes treated with HOE,  positive and negative controls (Mean ± SE)
Fig. 4. Determination of cleaved PARP and active caspase-3 levels by    ELISA. (A) Cleaved PARP levels in MCF-7 and MDA-MB-231 cell lines  after 72 h treatment with 100 µg/ml concentration of HOE

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