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藥學科技上課心得:黃子傑

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藥物化學報告(SCIFINDER、THOMSON Innovation)

黃子傑B303098221 藥三B

Explore references by research topic: XYLITOL Streptococcus mutans Candidates Selected (ID 1)

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Type: Effect of xylitol consumption on the plaque-saliva distribution of mutans streptococci and the occurrence and long-term survival of xylitol-resistant strains

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Explore references by research topic: XYLITOL Streptococcus mutans Candidates Selected (ID 1)

5 references were found containing "XYLITOL Streptococcus mutans " asentered. Answer Type: Answers

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Type: Effect of xylitol on mutans streptococci and lactic acid formation in saliva and plaque from adolescents and young adults with fixed orthodontic appliances

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蛀牙是文明社會中,口腔疾病的一個重要問題;故此,世界上對這個課題所做的 研究也不少,當中也發現不少有關於此方面的成果。好像蛀牙大多是由於變形鏈 球菌所引起之類的成果。所以,對於鏈球菌的抑製變了對抗蛀牙發生的好對策, 因此,使用含氟牙膏等方面的方法也隨之通用。但可惜局限於繁忙的社會,世界 上早、晚刷牙變了最基本、最極限的預防方法。故此,因應此方面的問題,對於 能夠隨時隨地進行預防的方法也應運而生。木糖醇正是一個好例子,其已在實驗 中取得對於鏈球菌有抑製的作用,現在發展在口香糖中添加木糖醇以預防蛀牙的 發生了。而在有關研究也顯示,其本身作用效果也能相應減低部分鏈球菌的滋生, 對於預防蛀牙的發生,無疑是有一定程度的幫助。而最主要的是添加在口香糖中 能夠不限時間的進行,是一個突破之處。 因應口香糖在現在社會的普及,除了是簡單的零食外,還有預防蛀牙的用途,故 此口香糖在社會上奠下了一個地位。因此,食用口香糖的人也不為少數,但隨之 而來的就是口香糖破壞環境的問題。由於口香糖在缺乏水分是具有黏性的,一旦 在不適宜的地方黏上,除了難以清除外,也破壞了美觀。故此,無黏性的口香糖 的發展也隨之進行。而早在十年前,已經有研究製出可無黏性的口香糖基質,可 代替過去的基質進行改善具黏性的情況。但是,成本卻成了最難解決的問題。由 於若製造無黏性的基質所費的時間、金錢也偏多,故仍未獲得社會上廣泛的應同。 因此,這方面的創新主要能在減低成本與材料的選擇,使製造能有一個更好的改 進方案。

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