SONUÇ VE ÖNERİLER

Özofagus atrezisinde torakotomi ve torakoskopi ile primer onarımın uzun dönem sonuçlarının karşılaştırıldığı bu çalışmada en önemli morbidite nedeni torakotomi sonrası gelişen göğüs deformiteleri olarak saptanmıştır.

Primer onarıma elverişli hastaları torakotominin getirdiği bu ve diğer komorbid durumlardan uzak tutmak için deneyimli ekibe sahip donanımlı merkezlerde ilk seçenek torakoskopik primer onarım olmalıdır.

8. KAYNAKLAR

1. van Lennep M, Singendonk MMJ, Dall’Oglio L, Gottrand F, Krishnan U, Terheggen- Lagro SWJ, et al. Oesophageal atresia. Nat Rev Dis Prim [Internet]. 2019;5(1):26. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31000707

2. Bax KMA. Esophageal Atresia and Tracheoesophageal Malformations [Internet]. 5th editio. Ashcraft’s Pediatric Surgery. Elsevier; 2010. 345–361 p. Available from: http://dx.doi.org/10.1016/B978-1-4160-6127-4.00027-6

3. Hollwarth M. Pediatric thoracic surgery. Vol. 25, Pediatric Surgery International. 2009. 1131 p.

4. Spilde T, Bhatia A, Ostlie D, Marosky J, Holcomb G, Snyder C, et al. A role for sonic hedgehog signaling in the pathogenesis of human tracheoesophageal fistula. J Pediatr Surg. 2003;38(3):465–8.

5. Arsic D, Cameron V, Ellmers L, Quan QB, Keenan J, Beasley S. Adriamycin disruption of the Shh-Gli pathway is associated with abnormalities of foregut development. J Pediatr Surg. 2004;39(12):1747–53.

6. Zimmer J, Eaton S, Murchison LE, De Coppi P, Ure BM, Dingemann C. State of Play: Eight Decades of Surgery for Esophageal Atresia. Eur J Pediatr Surg. 2019;29(1):39– 48.

7. Alberti D, Boroni G, Corasaniti L, Torri F. Esophageal atresia: Pre and post-operative management. J Matern Neonatal Med. 2011;24(SUPPL. 1):4–6.

8. Holcomb GW, Rothenberg SS, Bax KMA, Martinez-Ferro M, Albanese CT, Ostlie DJ, et al. Thoracoscopic repair of esophageal atresia and tracheoesophageal fistula: A multi-institutional analysis. Ann Surg. 2005;242(3):422–30.

9. LOBE TE, ROTHENBERG S, WALDSCHMIDT J, STROEDTER L. Thoracoscopic Repair of Esophageal Atresia in an Infant: A Surgical First. Pediatr Endosurgery Innov Tech [Internet]. 1999 Jan;3(3):141–8. Available from:

https://www.liebertpub.com/doi/10.1089/pei.1999.3.141

10. Davenport M, Rothenberg SS, Crabbe DCG, Wulkan ML. The great debate: Open or thoracoscopic repair for oesophageal atresia or diaphragmatic hernia. J Pediatr Surg [Internet]. 2015;50(2):240–6. Available from:

http://dx.doi.org/10.1016/j.jpedsurg.2014.11.008

11. Muensterer OJ, Sterlin A, Oetzmann von Sochaczewski C, Lindner A, Heimann A, Balus A, et al. An experimental study on magnetic esophageal compression

anastomosis in piglets. J Pediatr Surg [Internet]. 2020;55(3):425–32. Available from: https://doi.org/10.1016/j.jpedsurg.2019.04.029

12. Bairdain S, Hamilton TE, Smithers CJ, Manfredi M, Ngo P, Gallagher D, et al. Foker process for the correction of long gap esophageal atresia: Primary treatment versus secondary treatment after prior esophageal surgery. J Pediatr Surg [Internet].

2015;50(6):933–7. Available from: http://dx.doi.org/10.1016/j.jpedsurg.2015.03.010 13. Lugo B, Malhotra A, Guner Y, Nguyen T, Ford H, Nguyen NX. Thoracoscopic versus

open repair of tracheoesophageal fistula and esophageal atresia. J Laparoendosc Adv Surg Tech. 2008;18(5):753–6.

14. Borruto F, Impellizzeri P, Montalto A, Antonuccio P, Santacaterina E, Scalfari G, et al. Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula repair: Review of the literature and meta-analysis. Eur J Pediatr Surg. 2012;22(6):415– 9.

15. Way C, Wayne C, Grandpierre V, Harrison BJ, Travis N, Nasr A. Thoracoscopy vs. thoracotomy for the repair of esophageal atresia and tracheoesophageal fistula: a systematic review and meta-analysis. Pediatr Surg Int [Internet]. 2019;35(11):1167–84. Available from: https://doi.org/10.1007/s00383-019-04527-9

16. Spitz L. Oesophageal atresia. Vol. 2, Orphanet Journal of Rare Diseases. BioMed Central; 2007. p. 24.

17. Spitz L. Esophageal atresia. Lessons I have learned in a 40-year experience. J Pediatr Surg. 2006;41(10):1635–40.

18. Nguyen T, Zainabadi K, Bui T, Emil S, Gelfand D, Nguyen N. Thoracoscopic Repair of Esophageal Atresia and Tracheoesophageal Fistula: Lessons Learned. J

Laparoendosc Adv Surg Tech [Internet]. 2006 Apr;16(2):174–8. Available from: http://link.springer.com/10.1007/978-3-642-11202-7_16

19. Patkowski D, Rysiakiewicz K, Jaworski W, Zielinska M, Siejka G, Konsur K, et al. Thoracoscopic repair of tracheoesophageal fistula and esophageal atresia. J

Laparoendosc Adv Surg Tech. 2009;19(SUPPL. 1):19–22.

20. Waterston DJ, Carter REB, Aberdeen E. ŒSOPHAGEAL ATRESIA: TRACHEO- ŒSOPHAGEAL FISTULA. A Study of Survival in 218 Infants. Lancet.

1962;279(7234):819–22.

21. Spitz L, Kiely EM, Morecroft JA, Drake DP. Oesophageal atresia: At-risk groups for the 1990s. J Pediatr Surg. 1994;29(6):723–5.

22. Dingemann C, Zoeller C, Ure B. Thoracoscopic repair of oesophageal atresia: Results of a selective approach. Eur J Pediatr Surg. 2013;23(1):14–8.

Surg. 2012;36(9):2093–7.

24. Svoboda E, Fruithof JA, Widenmann-Grolig A, Slater G, Armand F, Warner B, et al. A patient led, international study of long term outcomes of esophageal atresia: EAT 1. J Pediatr Surg [Internet]. 2018;53(4):610–5. Available from:

https://doi.org/10.1016/j.jpedsurg.2017.05.033

25. Stadil T, Koivusalo A, Pakarinen M, Mikkelsen A, Emblem R, Svensson JF, et al. Surgical repair of long-gap esophageal atresia: A retrospective study comparing the management of long-gap esophageal atresia in the Nordic countries. J Pediatr Surg. 2019;54(3):423–8.

26. Friedmacher F, Kroneis B, Huber-Zeyringer A, Schober P, Till H, Sauer H, et al. Postoperative Complications and Functional Outcome after Esophageal Atresia Repair: Results from Longitudinal Single-Center Follow-Up. J Gastrointest Surg.

2017;21(6):927–35.

27. Von Allmen D, Wijnen RMH. Bridging the Gap in the Repair of Long-Gap Esophageal Atresia: Still Questions on Diagnostics and Treatment. Eur J Pediatr Surg.

2015;25(4):312–7.

28. Liu J, Yang Y, Zheng C, Dong R, Zheng S. Surgical outcomes of different approaches to esophageal replacement in long-gap esophageal atresia. Med (United States). 2017;96(21).

29. Tan Tanny SP, Comella A, Hutson JM, Omari TI, Teague WJ, King SK. Quality of life assessment in esophageal atresia patients: a systematic review focusing on long-gap esophageal atresia. J Pediatr Surg. 2019;

30. Spitz L. Esophageal replacement: Overcoming the need. J Pediatr Surg [Internet]. 2014;49(6):849–52. Available from: http://dx.doi.org/10.1016/j.jpedsurg.2014.01.011 31. Naik-Mathuria BJ, Rosenfeld EH, Gosain A, Burd R, Falcone RA, Thakkar R, et al.

Proposed clinical pathway for nonoperative management of high-grade pediatric pancreatic injuries based on a multicenter analysis: A pediatric trauma society collaborative. J Trauma Acute Care Surg. 2017;83(4):589–96.

32. Amin R, Knezevich M, Lingongo M, Szabo A, Yin Z, Oldham KT, et al. Long-term Quality of Life in Neonatal Surgical Disease. Ann Surg. 2018;268(3):497–505. 33. Leibovitch L, Zohar I, Maayan-Mazger A, Mazkereth R, Strauss T, Bilik R. Infants

born with esophageal atresia with or without tracheo-esophageal fistula: Short-and long-term outcomes. Isr Med Assoc J. 2018;20(3):161–6.

34. Onyeador N, Paul SP, Sandhu BK. Paediatric gastroesophageal reflux clinical practice guidelines. Vol. 99, Archives of Disease in Childhood: Education and Practice Edition.

2014. 190–193 p.

35. Ziolkowski N, Kitto SC, Jeong D, Zuccaro J, Adams-Webber T, Miroshnychenko A, et al. Psychosocial and quality of life impact of scars in the surgical, traumatic and burn populations: A scoping review protocol. BMJ Open. 2019;9(6):1–6.

36. Flieder S, Dellenmark-Blom M, Witt S, Dingemann C, Quitmann JH, Jönsson L, et al. Generic Health-Related Quality of Life after Repair of Esophageal Atresia and Its Determinants within a German-Swedish Cohort. Eur J Pediatr Surg. 2019;29(1):75–84. 37. Lechien JR, Cavelier G, Thill MP, Huet K, Harmegnies B, Bousard L, et al. Validity

and reliability of the French version of Eating Assessment Tool (EAT-10). Eur Arch Oto-Rhino-Laryngology. 2019;276(6):1727–36.

38. Rosenbek JC, Robbins JA, Roecker EB, Coyle JL, Wood JL. A penetration-aspiration scale. Dysphagia [Internet]. 1996;11(2):93–8. Available from:

http://link.springer.com/10.1007/BF00417897

39. Langmore SE, Kenneth SMA, Olsen N. Fiberoptic endoscopic examination of swallowing safety: A new procedure. Dysphagia [Internet]. 1988 Dec;2(4):216–9. Available from: http://link.springer.com/10.1007/BF02414429

40. Working group of ESPGHAN. A Standardized Protocol for the Methodology of Esophageal pH Monitoring and Interpretation of the Data for the Diagnosis of Gastroesophageal Reflux. J Pediatr Gastroenterol Nutr [Internet]. 1992

May;14(4):467–71. Available from: http://journals.lww.com/00005176-199205000- 00017

41. Jamieson JR, Stein HJ, DeMeester TR, Bonavina L, Schwizer W, Hinder RA, et al. Ambulatory 24-h esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility. Am J Gastroenterol [Internet]. 1992 Sep;87(9):1102—1111. Available from: http://europepmc.org/abstract/MED/1519566 42. Brasfield D. The Chest Roentgenogram Scoring System. 1979;63(1).

43. Oostveen E, MacLeod D, Lorino H, Farré R, Hantos Z, Desager K, et al. The forced oscillation technique in clinical practice: Methodology, recommendations and future developments. Eur Respir J. 2003;22(6):1026–41.

44. Komarow HD, Myles IA, Uzzaman A, Metcalfe DD. Impulse oscillometry in the evaluation of diseases of the airways in children. Ann Allergy, Asthma Immunol [Internet]. 2011;106(3):191–9. Available from:

46. Ziegler EE. 4.2 The CDC and euro growth charts. World Rev Nutr Diet. 2015;113:295–307.

47. Varni JW, Seid M, Kurtin PS. PedsQLTM 4.0: Reliability and Validity of the Pediatric Quality of Life InventoryTM Version 4.0 Generic Core Scales in Healthy and Patient Populations. Med Care. 2001;39(8):800–12.

48. Varni JW, Limbers CA, Burwinkle TM. Impaired health-related quality of life in children and adolescents with chronic conditions: A comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQLTM 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5.

49. Lawal TA, Gosemann JH, Kuebler JF, Glüer S, Ure BM. Thoracoscopy Versus Thoracotomy Improves Midterm Musculoskeletal Status and Cosmesis in Infants and Children. Ann Thorac Surg [Internet]. 2009;87(1):224–8. Available from:

http://dx.doi.org/10.1016/j.athoracsur.2008.08.069

50. Lacher M, Froehlich S, Von Schweinitz D, Dietz HG. Early and long term outcome in children with esophageal atresia treated over the last 22 years. Klin Padiatr.

2010;222(5):296–301.

51. Little DC, Rescorla FJ, Grosfeld JL, West KW, Scherer LR, Engum SA. Long-term analysis of children with esophageal atresia and tracheoesophageal fistula. J Pediatr Surg. 2003;38(6):852–6.

52. Somppi E, Tammela O, Ruuska T, Rahnasto J, Laitinen J, Turjanmaa V, et al. Outcome of patients operated on for esophageal atresia: 30 years’ experience. J Pediatr Surg. 1998;33(9):1341–6.

53. Tambucci R, Angelino G, De Angelis P, Torroni F, Caldaro T, Balassone V, et al. Anastomotic strictures after esophageal atresia repair: Incidence, investigations, and management, including treatment of refractory and recurrent strictures. Vol. 5, Frontiers in Pediatrics. 2017.

54. Sistonen S, Malmberg P, Malmström K, Haahtela T, Sarna S, Rintala RJ, et al.

Repaired oesophageal atresia: Respiratory morbidity and pulmonary function in adults. Eur Respir J. 2010;36(5):1106–12.

55. Mortell AE, Azizkhan RG. Esophageal atresia repair with thoracotomy: the Cincinnati contemporary experience. Semin Pediatr Surg [Internet]. 2009;18(1):12–9. Available from: http://dx.doi.org/10.1053/j.sempedsurg.2008.10.003

56. Smithers CJ, Hamilton TE, Manfredi MA, Rhein L, Ngo P, Gallagher D, et al. Categorization and repair of recurrent and acquired tracheoesophageal fistulae

Available from: http://dx.doi.org/10.1016/j.jpedsurg.2016.08.012

57. Rommel N, Rayyan M, Scheerens C, Omari T. The potential benefits of applying recent advances in esophageal motility testing in patients with esophageal atresia. Front Pediatr. 2017;5(June):1–7.

58. Rayyan M, Rommel N, Tack J, Deprest J, Allegaert K. Esophageal Atresia : Future Directions for Research on the Digestive Tract. 2016;

59. Tovar JA, Fragoso AC. Gastroesophageal reflux after repair of esophageal atresia. Eur J Pediatr Surg. 2013;23(3):175–81.

60. Holland AJA, Fitzgerald DA. Oesophageal atresia and tracheo-oesophageal fistula: current management strategies and complications. Paediatr Respir Rev [Internet]. 2010;11(2):100–7. Available from: http://dx.doi.org/10.1016/j.prrv.2010.01.007 61. Jaureguizar E, Vazquez J, Murcia J, Diez Pardo JA, Juniper EF. Morbid

musculoskeletal sequelae of thoracotomy for tracheoesophageal fistula. J Pediatr Surg. 1997;20(2):511–4.

62. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–38.

63. Faure C, Grunder FR. Dysmotility in esophageal atresia: Pathophysiology, characterization, and treatment. Front Pediatr. 2017;5(May):1–6.

64. Wu Y, Kuang H, Lv T, Wu C. Comparison of clinical outcomes between open and thoracoscopic repair for esophageal atresia with tracheoesophageal fistula: a systematic review and meta-analysis. Pediatr Surg Int. 2017;33(11):1147–57.

65. Koivusalo A, Pakarinen MP, Turunen P, Saarikoski H, Lindahl H, Rintala RJ. Health- related quality of life in adult patients with esophageal atresia - A questionnaire study. J Pediatr Surg. 2005;40(2):307–12.

66. Maghsoudlou P, Eaton S, De Coppi P. Tissue engineering of the esophagus. Semin Pediatr Surg [Internet]. 2014;23(3):127–34. Available from:

9. EKLER

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