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A case of myocardial bridging of the left circumflex coronary arterySol sirkumfleks koroner arterde miyokardiyal köprüleşme: Olgu sunumu

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562 Türk Kardiyol Dern Arş - Arch Turk Soc Cardiol 2008;36(8):562-563

Myocardial bridge is a cluster of myocardial fibers crossing over the epicardial coronary arteries at a distance. Myocardial bridging most frequently occurs on the left anterior descending artery (LAD) and may lead to ischemia and related complications. Involvement of the left circumflex artery is very rare. Herein, we present a symptomatic case of circumflex coronary artery bridging.

CASE REPORT

A 63-year-old man presented to our clinic because of chest pain radiating to the left shoulder. Physical examination was normal. Blood pressure and car-diac rate were in normal ranges. The electrocar-diogram showed slight lateral ST-segment changes. Echocardiography was normal. Treadmill electro-cardiography revealed significant lateral ST and T wave changes. Cardiac catheterization showed normal coronary arteries except for significant systolic

nar-rowing of the mid-circumflex artery after the first obtuse marginal branch (Fig. 1). Symptomatic relief was achieved after beta-blocker therapy. He was followed-up uneventfully for eight months.

DISCUSSION

Myocardial bridging is characterized by systolic compression of the tunneled segment, which remains clinically silent in the vast majority of cases.[1] The

bridging appears on angiography as systolic narrow-ing or complete obliteration of the arterial lumen, while the lumen is normal during diastole. Its preva-lence shows substantial variation, being higher at autopsy than angiography. Compared to angiographic depiction of less than 5%, myocardial bridges are thought to exist in about one-third of adults.[1] In the

vast majority of cases, angiographic localization of myocardial bridges is the LAD.[2] Localizations other

than the LAD are extremely rare.[3-6]

A case of myocardial bridging of the left circumflex coronary artery

Sol sirkumfleks koroner arterde miyokardiyal köprüleşme: Olgu sunumu

Cemal Tuncer, M.D., Gülizar Sökmen, M.D., Gürkan Acar, M.D., Sedat Köroğlu, M.D.

Department of Cardiology, Medicine Faculty of Kahramanmaraş Sütçü İmam University, Kahramanmaraş

Received: November 24, 2007 Accepted: January 31, 2008

Correspondence: Dr. Sedat Köroğlu. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Hanefi Öksüz Kalp Hastanesi, 46100 Kahramanmaraş, Turkey. Tel: +90 344 - 221 23 37 Fax: +90 344 - 221 72 39 e-mail: m.sedatkoroglu@gmail.com Myocardial bridge is a cluster of myocardial fibers

cross-ing over the epicardial coronary arteries at a distance. It is most frequently seen on the left anterior descending artery. Involvement of the left circumflex coronary artery is very rare. A 63-year-old man presented with chest pain radiat-ing to the left shoulder. Physical examination was normal. The electrocardiogram showed slight lateral ST-segment changes. Treadmill electrocardiography revealed signifi-cant lateral ST and T wave changes. Coronary angiogra-phy showed normal coronary arteries except for significant systolic narrowing of the mid-circumflex artery after the first obtuse marginal branch. The patient was discharged with beta-blocker therapy. He had no recurrent chest pain during eight months of follow-up.

Key words: Coronary angiography; coronary vessel

anoma-lies/diagnosis/therapy.

Miyokardiyal köprüleme epikardiyal koroner arterlerin belirli mesafelerde üzerinden geçen kas lifi demetle-rinden oluşur. En sık olarak sol ön inen arter üzerinde görülür. Sol sirkumfleks arterde görülmesi çok nadir-dir. Altmış üç yaşında erkek hasta sol omza yayılan göğüs ağrısı yakınmasıyla başvurdu. Fizik muayenesi normal olan hastanın elektrokardiyogramında lateral ST-segment değişiklikleri izlendi. Egzersiz elektrokar-diyogramda belirgin lateral ST ve T dalga değişiklikleri gözlendi. Koroner anjiyografide, birinci obtus marjinden sonra sirkumfleks arterin ortasında sistolik daralma dışında koroner arterler normal bulundu. Hasta beta-bloker tedavisi ile taburcu edildi. Sekiz aylık takip döne-minde göğüs ağrısı tekrarlamadı.

Anah tar söz cük ler: Koroner anjiyografi; koroner damar

(2)

A case of myocardial bridging of the left circumflex coronary artery 563

Arjomand et al.[5] reported the first case of

myocar-dial bridging of the circumflex artery (mid-portion) associated with acute myocardial infarction. Ischemia due to myocardial bridging of a coronary artery may occur by several mechanisms, including systolic com-pression of the tunneled segment, increased sympa-thetic drive during stress or exercise, endothelial dys-function, coronary artery spasm, and systolic kinking of the artery.[7-10] Clinically, myocardial bridges may

present as atypical or angina-like chest pain with no consistent association between symptom severity and the length or depth of the tunneled segment or the degree of systolic compression.[11] The risk for serious

clinical consequences is low if associated symptoms and ischemia are timely and appropriately treated. No treatment may be required in asymptomatic patients. The approach to patients having myocardial bridges in the LAD may be extrapolated to those with non-LAD myocardial bridges. There are three poten-tial therapeutic strategies including pharmacological treatment, surgery (myotomy or bypass grafting), and percutaneous coronary intervention.

In conclusion, although myocardial bridges most commonly involve the LAD, non-LAD myocardial bridges should be borne in mind in symptomatic patients. In our case, the symptoms were completely relieved with beta-blocker therapy.

REFERENCES

1. Mohlenkamp S, Hort W, Ge J, Erbel R. Update on myo-cardial bridging. Circulation 2002;106:2616-22.

2. Bourassa MG, Butnaru A, Lesperance J, Tardif JC. Symptomatic myocardial bridges: overview of ischemic

mechanisms and current diagnostic and treatment strate-gies. J Am Coll Cardiol 2003;41:351-9.

3. Okmen E, Oguz E, Erdinler I, Sanli A, Cam N. Left cir-cumflex coronary artery bridging. Jpn Heart J 2002;43: 423-7.

4. Woldow AB, Goldstein S, Yazdanfar S. Angiographic evidence of right coronary bridging. Cathet Cardiovasc Diagn 1994;32:351-3.

5. Arjomand H, AlSalman J, Azain J, Amin D. Myocardial bridging of left circumflex coronary artery associated with acute myocardial infarction. J Invasive Cardiol 2000; 12:431-4.

6. Garg S, Brodison A, Chauhan A. Occlusive systolic bridging of circumflex artery. Catheter Cardiovasc Interv 2000;51:477-8.

7. Ge J, Jeremias A, Rupp A, Abels M, Baumgart D, Liu F, et al. New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. Eur Heart J 1999;20:1707-16.

8. Klues HG, Schwarz ER, vom Dahl J, Reffelmann T, Reul H, Potthast K, et al. Disturbed intracoronary hemodynamics in myocardial bridging: early normal-ization by intracoronary stent placement. Circulation 1997;96:2905-13.

9. Morales AR, Romanelli R, Tate LG, Boucek RJ, de Marchena E. Intramural left anterior descending coro-nary artery: significance of the depth of the muscular tunnel. Hum Pathol 1993;24:693-701.

10. Noble J, Bourassa MG, Petitclerc R, Dyrda I. Myocardial bridging and milking effect of the left anterior descend-ing coronary artery: normal variant or obstruction? Am J Cardiol 1976;37:993-9.

11. Ferreira AG Jr, Trotter SE, König B Jr, Decourt LV, Fox K, Olsen EG. Myocardial bridges: morphological and functional aspects. Br Heart J 1991;66:364-7.

Figure 1. Successive frames from the left lateral view showing significant systolic narrowing of the mid-circumflex (Cx) artery after the first obtuse marginal branch. LAD: Left anterior descending artery.

Referanslar

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