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The Effects of Regular Exercise Training on Body Composition, Cardiorespiratory Fitness, and Blood Biochemical Index in Subjects with Metabolic Syndrome

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規律運動訓練對代謝症候群個案身體組成、心肺適能與血液生化值成

效之探討

The Effects of Regular Exercise Training on Body Composition, Cardiorespiratory Fitness, and Blood Biochemical Index in Subjects with Metabolic Syndrome

中文摘要 論文摘要

論文名稱:規律運動訓練對代謝症候群個案身體組成、心肺適能與血 液生化值成效之探討

研究所名稱:臺北醫學大學護理學研究所 研究生姓名:謝長華

畢業時間:九十四學年度第二學期

指導教授:蔡仁貞 臺北醫學大學護理研究所教授

代謝症候群是心血管疾病許多危險因素聚集的現象,近年來許多學者研究發現肥 胖及久坐工作生活型態、飲食、基因遺傳、環境因素等可能是導致此症候群的原 因。而本研究的目的在探討規律運動訓練對代謝症候群個案身體組成、心肺適能 與血液生化值之成效。

本研究採類實驗設計法,以台北市某醫學中心 18-65 歲代謝症候群個案為對象,

本計畫先進行運動組之計畫,再招募對照組,共有 22 位完成此研究,其中運動 組與對照組各 11 人。運動組個案進行每週 3 次,每次 30 分鐘,共為期 12 週的 跑步機運動訓練,對照組則保持原有的生活型態。研究計畫前後以個案基本資料 表、血液分析、運動測試等進行資料收集。研究資料分別以百分比、平均值、標 準差、曼-惠特尼考驗(Mann-Whitney U test)、魏氏帶符號等級考驗(Wilcoxon signed ranks test)等統計方法進行分析。研究結果發現:(一)不同人口學特性 個案在代謝症候群危險因子,在不同學歷、抽菸有無與喝酒之個案在代謝症候群 危險因子並無顯著的差異。而男性腰臀圍比、VO2 max、靜態舒張壓、三酸甘油 酯皆高於女性;有工作者 VO2 max 高於無工作者;經濟況狀較優者,其 VO2max 愈高、血液中的總膽固醇、低密度脂蛋白膽固醇含量也較高;具心血管家族史之

個案其空腹血糖值高於無心血管家族史者。(二)兩組個案在研究計畫前後,靜

態收縮壓之變化達顯著差異(p = .04),而運動組個案在代謝症候群危險因子中,

腰圍(p = .003)、腰臀圍比(p = .02)、VO2 max(p = .01)、靜態收縮壓(p = .04)、

靜態舒張壓(p = .02)、三酸甘油酯(p = .03),在 12 週的運動訓練後有顯著改

善的趨勢。(三)在代謝症候群診斷指標方面,運動組個案於研究計畫前有 11 位

符合代謝症候群≧3 項指標,在研究計畫後有 4 位(36.4%)不再屬於代謝症候 群。

(2)

本研究結果顯示,中高強度的規律運動訓練對改善代謝症候群之危險因子仍扮演 重要角色,護理人員可指導代謝症候群個案每週 3 次,每次 30 分鐘,為期 12 週以上中高強度之運動計畫。

關鍵字:代謝症候群、規律運動訓練、身體組成、心肺適能、胰島 素阻抗

英文摘要

Title of Thesis: The Effects of Regular Exercise Training Author:Chang-Hua Hsieh

Thesis directed by:Jen-Chen Tsai, Professor

Many scholars’ researches have found in recent years, the metabolic syndrome is mainly caused by cardiovascular risks factor such as sedentary life style, dietary factors, genetic factors, and environment factors etc.

The purpose of this study was set to evaluate effects of regular exercise training on body composition, cardiorespiration fitness, and blood biochemical index in subjects with metabolic syndrome.

A quasi-experimental design was used to guide the study. Subjects in this study were metabolic syndrome with age from 18-65. They were chosen from a medical center hospital in Taipei, Taiwan. Subjects were assigned into an exercise or a control group.

Complete data are available for 22 subjects in total, with 11 from exercise group and 11 from control group. The exercise group participated in a 12-weeks treadmill exercise program, three times each week, 30 minutes each time. The control group remained their living pattern. Data collected was mainly focusing on subjects’

personal data chart, blood biochemistry analysis, and exercise test. Data was analysed using percentage, mean, standard deviation, Fisher’s exact test, Mann-Whitney U test, and Wilcoxon signed ranks test.

Results: (1)There is no significant difference in metabolic syndrome research results on subjects’ educational background, and smoking or drinking habits. However, male subjects’ waist to hip ratio, VO2 max , and resting diastolic blood pressure are higher than those observed in female subjects. For those subjects who have a regular job, their VO2 max are significantly higher than those who are unemployed . Subjects with better economic status also have higher VO2 max , total cholesterol, and LDL-C levels than . Subjects with family history of cardiovascular disease have fasting plasma sugar that is higher than those who have no family history. (2)After 12 weeks, two groups had significant in their resting systolic blood pressure ( p = .04). However, exercisers have improvement in their waist circumference (p = .003), waist to hip ratio (p = .02), VO2 max (p = .01), resting systolic blood pressure (p = .04), resting

(3)

diastolic blood pressure (p = .02), and triglycerides (p = .03). (3)After 12 weeks, 4 exercisers (36.4%) no longer had metabolic syndrome.

This study has revealed that 12-week moderate to vigorous intensity regular exercise training may help subjectsts minimizing their cardiovascular risk factors of metabolic syndrome.

Key words: Metabolic Syndrome, Regular Exercise Training, Body Composition, Cardiorespiratory Fitness, Insulin Resistance.

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