• Sonuç bulunamadı

What is Drug Targeting?

N/A
N/A
Info
İndir
Protected

Academic year: 2021

Share "What is Drug Targeting?"

Copied!
9
0
0

Yükleniyor.... (view fulltext now)

Şimdi indir ( 9 sayfa )

Tam metin

(1)
(2)
(3)
(4)
(5)
(6)

Properties of İdeal Drug Delivery

Targeting

• It should be -o N-on-t-oxic o Biocompatible o Biodegradable

o Physicochemical stable both in-vivo & in-vitro • Controlled and predictable drug release

• Minimal drug leakage

• Carrier should be readily eliminated without causing any change in

diseased state

• Preparation should be easy, reproductive and cost effective • Drug release should not effect drug action

(7)
(8)
(9)

Briefly;

ADVANTAGES

• Reduction of drug side-effects

• Reduced frequency of drug intake

• Reduced dose of drug • Uniform blood level of drug

• Maximizes the therapeutic

index

DISADVANTAGES

• Rapid clearance of targeted systems

• Immune reaction against carrier systems

• Insufficient localization of targeted systems in tumor cells

• Diffusion and redistribution of released drug

Referanslar

Şimdi indir ( PDF - 9 sayfa - 708.82 KB )

Benzer Belgeler

Biodegradable Polymeric Nanoparticles are effective Systems for Controlled Drug Delivery

Polymeric nanoparticles have spesific properties. Their stability in gastrointestinal tract, protection ability for encapsulated drugs, modulated drug release properties

Applications of Polyhydroxyalkanoates in Drug Delivery

Etoposide (used as a drug) and Concanavalin-A (Con-A) (used to target cancer cells) were loaded onto the nanoparticles and the release kinetics of the drug evaluated..

DRUG DELIVERY AND

This relationship can be used to describe the drug dissolution of several types of modified release pharmaceutical dosage forms, as in the case of controlled release systems such as

DRUG DELIVERY AND

This system is a simplified form of the membrane permeation- controlled system. Here the drug reservior is formulated by directly dispersing the drug in an adhesive polymer...

Oral Controlled Drug Delivery Systems WEEK 12

independent release systems. However, most active substances have ionisation properties, these weakly acidic / weakly basic molecules or their salts show pH-dependent solubility...

DRUG DELIVERY AND

To prolong the retention time of topically applied drugs, anterior drug delivery systems for eye-drops utilizing interaction between drug carrier (excipients) and

DRUG DELIVERY AND

In recent years many drugs have been shown to achieve better systemic bioavailability through nasal route than by oral administration... ➢ It is a useful delivery route for drugs

Drug Delivery

• NDDS is advanced drug delivery system which improves drug potency, control drug release to give a sustained therapeutic effect, provide greater safety, finally it is to target