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Cardiac metastasis of an esophageal cancer: a rare cause of ventricular tachycardia and left ventricle outlet obstruction

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Özcan Başaran Can Yücel Karabay#

Ahmet Güler#

Cevat Kırma#

Department of Cardiology, Mugla University Training and Research Hospital, Mugla;

#Department of Cardiology,

Kartal Kosuyolu Training and Research Hospital, Istanbul

Türk Kardiyol Dern Arş - Arch Turk Soc Cardiol 2013;41(7):670 doi: 10.5543/tkda.2013.28475

An 80-year-old woman was admitted to our hospital with palpita-tions and shortness of breath. She had been diagnosed with esopha-geal cancer (squamous cell carcinoma) one year ago. A physical examination revealed a 2/6 systolic mur-mur on the left sternal border. Her pulse was weak and irregular at a rate of 170 bpm. Her blood pressure was taken as 90/50 mmHg. An ECG showed wide QRS complexes. She was diagnosed with ven-tricular tachycardia. As the patient was symptomatic, DC cardioversion was performed, and sinus rhythm was restored. Echocardiographic examination showed

left atrial and ventricular cardiac mass (Fig. A). A de-tailed examination showed the tumor had a direct ex-tension to the pericardium and had invaded all of the cardiac layers (Fig. A and supplementary Video 1*). Intracardiac masses were detected in the left and right atria and left ventricle. The tumor in the left ventricle appeared to be a solitary metastasis and was protrud-ing through the left ventricle outlet (Figs. B-D and supplementary Videos 2-4*). Amiodarone therapy was initiated and the patient was referred to oncology but she died the following day. We hypothesized that the mass in the left and right atria was a direct ex-tension or a lymphatic spread of the tumor, while the solitary left ventricular mass was probably an intra-cavitary diffusion of the tumor from pulmonary veins. Hematopoietic myocardial metastasis might also have played a role in the metastasis of the tumor as conduc-tion system abnormalities were associated with myo-cardial metastasis.

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Cardiac metastasis of an esophageal cancer:

a rare cause of ventricular tachycardia and left ventricle outlet obstruction

Özofagus kanserinin kalbe metastazı: Ventriküler taşikardi ve sol ventrikül çıkış yolu obstrüksiyonunun nadir bir nedeni

Figures– Transthoracic echocardiography of the patient. (A) Subcostal view: Arrows showing the mass infiltrating all three cardiac layers. (B) Modi-fied parasternal short-ax-is view showing left atrial (dotted line) and left ven-tricular outlet mass (star).

(C, D) Apical four-cham-ber and long-axis views showing left and right atrial mass (dotted line) and left ventricle outlet obstruction by the mass (arrows).

*Supplementa-ry video files associated with this presentation can be found in the online version of the journal. A

C

B

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