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Copyright © 2011 American Chemical Society (ACS). All Rights Reserved.

2. Study on synthesis of benzocaine in laboratory

By: Ding, Chang-ze

Source: Dangdai Huagong

,

Volume: 38

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Issue: 3

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Pages: 228-229, 271

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Journal

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2009

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CODEN: DHAUB9

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ISSN: 1671-0460

Company/Organization: Department of Chemistry and Material Science

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Hunan Institute of the Humanities and Science and Technology

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Hunan, Loudi, Peop. Rep. China, 417000

Accession Number: 2009:1124406

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CAN 152:476467

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CAPLUS Publisher: Dangdai Huagong Zazhishe

Language: Chinese

Abstract

Benzocaine is generally synthesized by oxidn., esterification and reducing reaction from p-nitrotoluene. In this paper, the synthesis of benzocaine from p-nitrotoluene using KMnO4 as oxidant, SnCl4 as catalyst and H2 as reducer was

investigated. The results show that the yield of benzocaine can get to 70.3% under the optimal condition. Indexing

History, Education, and Documentation (Section 20-4) Section cross-reference(s): 21

Supplementary Terms

chem; education; lab; synthesis; benzocaine; oxidn; esterification; redn;

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