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Translation and proteins

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Translation and proteins

Prof. Dr. İsmail AKYOL Prof. Dr. M. Ali YILDIZ Prof. Dr. M. Muhip ÖZKAN

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Outline of course

• The ribonucleotide sequence of messenger RNA (mRNA) reflects genetic information stored in the DNA of genes and corresponds to the amino acid sequences in proteins encoded by those genes.

• The process of translation decodes the information in mRNA, leading to the synthesis of polypeptide chains.

• Translation involves the interactions of mRNA, tRNA, ribosomes, and a variety of translation factors essential to the initiation, elongation,

and termination of the polypeptide chain.

• Proteins achieve a three-dimensional conformation that arises from the primary amino acid sequences of the polypeptide chains making up each protein.

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TRANSCRIPTION RNA PROCESSING RNA transcript 5Exon NUCLEUS FORMATION OF INITIATION COMPLEX CYTOPLASM 3DNA RNA polymerase RNA transcript (pre-mRNA) Intron Aminoacyl-tRNA synthetase Amino acid tRNA

AMINO ACID ACTIVATION

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