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FORCES INVOLVED

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(1)

DRUG-RECEPTOR INTERACTIONS FORCES INVOLVED

PHARMACEUTICAL CHEMISTRY I

PHA385

(2)

A receptor is a biological molecule

that yield a biological response

upon interaction with a drug

molecule

(3)

Biological response is produced by the interaction of a drug with a functional or organized group of molecules, which may be called the

biologic

(4)

Bonding forces between ligands and receptors

(5)
(6)

• Dipole-Dipole Interactions -Hydrogen bonding

-Charge transfer bonding -Hydrophobic bonding

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