中文摘要

靈芝之成分研究

 中文摘要

 靈芝是一種著名的中國草藥，在亞洲靈芝已廣泛地被使用 於保健以及延年益壽。近年來，亞太各國已把焦點放在中 草藥的發展研究，而靈芝是其中之一。靈芝含有多種化學 成分，其相關的藥理作用雖已被廣泛探討，但市售產品非 常混亂，在品質管制方面缺乏可供作指標成分者，因此，

本論文對靈芝所含之化學成分作進一步的研究，以便作為 靈芝製備之參考化合物。

 靈芝之子實體在室溫時以甲醇萃取，經過各種層析管柱分

離及純化分離後，初步得到九個化合物，其結構經由光譜

分析鑑定之後，確認為 Ganodermic acid G (1), Lucidone A

(2), Pachymic acid (3), Polyporenic acid C (4), Stellasterol (5),

Pterocarpin (6), Trifolirhizin (7), Kuraridinol (8), Kuraridin

(9) 。



英文摘要



Ganoderma lucidum (Fr.) karst ( polyporaceae ) is a well-known Chinese c

rude drug which has been widely used for promotion of health and longevit

y in East Asia. Current trend of phytotherapy research prevailing in Asia p

acific country, Ganoderma lucidum is one of the focal point in the develop

ment of Chinese herbs. Ganoderma lucidum contains several chemical con

stituents, which have been investigated in relation to their physiological eff

ects. The compounds can be used the standards in QC and the reference co

nstituents in preparation of standards. Therefore, a chemical investigation o

f compounds in Ganoderma lucidum was performed. The fruit body of Gan

oderma lucidum was extracted with MeOH at room temperature. By means

of various chromatographic methods, nine compound were isolated and pu

rified. On the basis of spectral analysis, the structure of this compound was

determined to be Ganodermic acid G (1), Lucidone A (2), Pachymic acid

(3), Polyporenic acid C (4), Stellasterol (5), Pterocarpin (6), Trifolirhizin

(7), Kuraridinol (8), Kuraridin (9) 。