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Local subcutaneous atrophy after occipital nerve block

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PAINA RI

53 JANUARY 2019

L E T T E R T O T H E E D I T O R

1Department of Physical Medicine and Rehabilitation, Patnos State Hospital, Ağrı, Turkey 2Department of Neurology, Fırat University Faculty of Medicine, Elazığ, Turkey

Submitted: 12.01.2018 Accepted after revision: 11.09.2018 Available online date: 13.12.2018

Correspondence: Dr. Samet Sancar Kaya. Patnos Devlet Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Ağrı, Turkey. Phone: +90 - 505 - 753 60 59 e-mail: sametsancarkaya@hotmail.com

© 2019 Turkish Society of Algology

To the Editor,

Local corticosteroid injections are commonly used to reduce inflammation and pain in joints, ligaments, tendons and other soft tissues. In addition, nerve blockade with corticosteroids (CS) has an impor-tant role in the treatment of headache. Nerve blocks made by combination of local anesthetic and CS duce inflammation, inhibiting nerve compaction, re-ducing the amount of nociceptive chemical media-tors and suppressing abnormal electrical activity in damaged nerves.[1]

A 15-year-old male patient underwent right occipita-lis major nerve blockade (12.86 mg Betamethasone dipropionate + 5.26 mg Betamethasone sodium phosphate + 10 mg lidocaine HCl) for cluster-type headache. One month after the injection, the pa-tient was admitted with a complaint of pitting in the area where the injection was made. The patient un-derwent injection of anatomical alopecia and a 3 cm diameter circular full-thickness soft tissue atrophy. Full-thickness atrophy of scalp was observed in cra-nial computed tomography and no pathology was observed in adjacent bone cortex.

Local CS injections can have many side effects such as infection, bleeding, flushing, hypersensitivity re-actions, tendon ruptures, hypopigmentation and soft tissue atrophy. The risk of soft tissue atrophy is less than 1%.[2] It usually develops within 1–4 months

after injection and recovers within a year. Surgical treatments such as fat tissue injection or grafting can be considered as atrophy longer than one year.[3]

While all CS injections can cause soft tissue atrophy, fluorogenic CS are more likely to cause soft tissue at-rophy due to their stable, low-resolution, and long-acting effects. For this reason, such as triamcinolone hexacetonide and triamcinolone acetonide, which are long-acting and low-resolution CS, are more suit-able for use in large joints and deep structures such as the knees, shoulders and elbows. It is suggested that betamethasone sodium and dexamethasone with higher resolution be used in more superficial structures such as bursa, tendon sheath, metacar-pophalangeal joint, interphalangeal joint and carpal tunnel.

The place where the nervus occipitalis major block is applied is the neighborhood where the trapezius and semispinalis capitis muscles attach to the oc-ciput. These muscles and aponeuros, as well as fat tissue may go into atrophy by injecting high doses of long-acting storage steroids.

Although side effects of CS injections are rare, pa-tients should be informed about these side effects.

References

1. Portenoy RK, Foley KM, Inturrisi CE. The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions. Pain 1990;43(3):273–86.

2. Papadopoulos PJ, Edison JD. The Clinical Picture - Soft tis-sue atrophy after corticosteroid injection. Cleve Clin J Med 2009;76(6):373–4.

3. Imagawa K, Ohkuma S. A case of fat injection for treating subcutaneous atrophy caused by local administration of corticosteroid. Tokai J Exp Clin Med 2010;35(2):66–9.

Local subcutaneous atrophy after occipital nerve block

Oksipital sinir blokajı sonrası gelişen lokal subkutanöz atrofi

Samet Sancar KAYA,1 Ferhat BALGETIR2

Agri 2019;31(1):53

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