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KanTransfüzyonEndikasyon

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KAN ve KAN ÜRÜNLERİ

TRANSFÜZYONU ENDİKASYONLARI

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Kan ve Kan Ürünleri Transfüzyonu

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Kan ve Kan Ürünleri Transfüzyonu

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Kanamaların sınıflandırılması

Derece Kan Kaybı Klinik

1.

< %15

Hafif hemodinamik etki

2.

%15-30

Taşikardi, nabız basıncında düşme, anksiyete

3.

%30-40

Belirgin taşikardi, takipne sistolik hipotansiyon,

bilinç bozukluğu

4.

> %40

Belirgin taşikardi, belirgin hipotansiyon, nabız

basıncında daralma, idrar atılımı azalması,

bilinçte depresyon

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Kanama Miktarının Tespiti

Şok İndeksi

KAH (atım/dk) / SAB (mmHg)]

Şok

İndeksi

İntravasküler

volum kaybı

~ 0.5

0

~ 0.8

% 10 – 20

~ 1.0

% 20 – 30

~ 1.1

% 30 – 40

~ 1.5

% 40 – 50

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Kan kaybına göre hipovolemik şokun klasifikasyonu

Hipovolemi

derecesi

I – Minimal II – Hafif

III – Orta

IV – Ciddi

Kan kaybı (%)

< %15

%15-30

%30-40

>%40

Kan kaybı (ml)

<750 ml

800 – 1500

ml

1500-2000 ml >2000 ml

SAB (mmHg)

N

N

Düşük

Çok düşük

DAB (mmHg)

N

Yüksek

Düşük

Çok düşük

NB (Atım/dk)

N

100-120

120-140

>140

Kapiller dolum

N

Yavaş (>2 sn) Yavaş (>2 sn)

Belirlenemez

Solunum hızı

N

N

Takipne

(>20/dk)

Takipne (>20/dk)

İdrar miktarı (ml/s)

30

20-30

5-10

Minimal

Perifer

N

Soluk

Soluk

Soluk, soğuk

Bilinç durumu

N

Huzursuz,

agresif

Huzursuz,

agresif, uykulu

Uykulu, konfüze

veya şuursuz

Cilt

N

Soluk

Soluk

Soluk

American College of Surgeons—Committee on Trauma: Shock. ATLS—Advanced Trauma Life Support for Doctors. Ed 6. Chicago, American College of Surgeons 87–107, 1997.

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Kanamada sıvı ve kan komponent tedavisi

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American Association of Blood Banks

Carson JL, et al (for the Clinical Transfusion Medicine Committee of the AABB). Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB. Ann Intern Med. 2012 Mar 26. [Epub ahead of print]

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Eritrosit Süspansiyonu

Garfinkle M, et al. Red blood cell transfusion and mortality among patients hospitalized for acute coronary syndromes: A

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Kan Ürünü Verilmesi

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Eritrosit Transfüzyonu Kanıt Uygulama

Cohen J, et al. Red blood cell transfusions--are we narrowing the evidence-practice gap? An observational study in 5 Israeli intensive care units. J Crit Care. 2011 Feb;26(1):106.e1-6.

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Trombosit Endikasyonları

ASA Klavuzu

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Human Albümin

Remahi MJT, et al. The Annals of Pharmacotherapy 2000;34:1198-1205. Yılmaz M, ve ark. Uluslararası Hematoloji-Onkoloji Dergisi.2006;16:18-22.

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Patients Blood Management

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Endikasyona Uyum

Yao YY, et al. [Investigation of the status of perioperative blood transfusion in grade III-A general

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Endikasyona Uyum

Flores-Paredes W. [To inadequate indication of blood transfusion in a reference hospital in Lima,

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Yerel Şartlarda Değişim

(Zonguldak Atatürk Devlet Hastanesi)

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Referanslar

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