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Comparison of the affective lability and temperament characteristics between depressive patients with and without mixed features

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E-Poster Presentation / European Psychiatry 56S (2019) S3–S321 S97

Unit, Muscat, Oman;4Oman Medical Speciality Board, Studies and

Research Section, Muscat, Oman

*Corresponding author.

Background and aims.– There is ample evidence to suggest that physical illness tend to impact on mental disorder and conversely mental disorder affect physical illness. There is a death of studies examine such link in societies in transition such as those in Oman. This study aims to determine the prevalence of depression and anx-iety among patients attending a rheumatology clinic in a tertiary care hospital in Oman. Related aims are to tease out the contribu-tion of demographic and clinical characteristics to the development of depression and anxiety.

Methods.– A cross-sectional study was conducted among atten-dees (n = 103) seeking consultation from a rheumatic unit. Depressive symptom and anxiety were assessed using Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disor-der (GAD-7) respectively. Data regarding demographic and clinical characteristics of respondents were collected.

Results.– The prevalence of depressive symptoms was 64% while 47% endorsed the presence of anxiety. 35% of respondents with depressive symptoms fulfil the criteria for moderately to severe depression. Approximately 27% of respondents with anxiety symp-toms found to have moderate to severe anxiety. Only 5% of patients with depression and 3% of patients with anxiety were receiving psychiatric treatment.

Conclusions.– This study collaborates with studies from other pop-ulations to support that the rate of psychiatric disorder is high among people with rheumatic diseases and it appears to exceed the rate found in the general population. Pending further scrutiny, mechanisms are needed in Oman to increase the awareness among physicians dealing with rheumatology patients. Such an undertak-ing could include providundertak-ing means for early detection and prompt interventions.

Disclosure of interest.– The authors have not supplied a conflict of interest statement.

E-PP0411

New initiatives of depression

management physician order at the

mental hospital of ministry of health

in Saudi Arabia

N. Alsolami1*, Y.A. Alomi1-2

1Al Amal Medical Complex, Pharmacy Department, Riyadh, Saudi

Arabia;2Ministry of Health, Pharmacy Department, Riyadh, Saudi

Arabia

*Corresponding author.

Background and aims.– The general administration of pharmaceuti-cal care stated evidence-based pharmacy guidelines at Ministry of Health hospitals and primary healthcare centers in 2015. The hos-pital started with a standard disease like depression. The tax force team designed the updated guidelines and approved by an official body in the hospital.

Methods.– The form friendly used and very important in preventing drug related problems and education system for healthcare staff. The depression physician order form consisted of patient demo-graphic data, the type or stage of disease, the first line of treatment, the dose and duration of therapy, and the second line of choice if existed. The co morbid disease with primary disease and appro-priate choice for each combined disease. The prescribed data and clinical pharmacist data as explored in the physician order form. Results.– Implementations steps of Depression management physi-cian Oder It is evidence-based setting up psychiatric therapeutic guidelines at the most prominent hospital a mental hospital at Min-istry of Health in Kingdom of Saudi Arabia. The guidelines based on evidence based on American psychiatric society recommendations. It designed through pharmacy task force team and headed by the

author. The guidelines implemented through several educational sessions with hospital staff. The manual physician order sent to information technology to convert as electronic physicians order entry

Conclusions.– The depression management therapy physician order is a new initiative program at the Mental hospital of Ministry of health in Saudi Arabia. The new project may prevent the drug-related problem and prevent economic burden in Healthcare system.

Disclosure of interest.– The authors have not supplied a conflict of interest statement.

E-PP0412

Comparison of the affective lability

and temperament characteristics

between depressive patients with and

without mixed features

K. Altinbas1*, H.I. Tas2

1Selcuk University Faculty of Medicine, Psychiatry- Mazhar Osman

Mood Clinic, Konya, Turkey;2Canakkale Onsekiz Mart University

Faculty of Medicine, Psychiatry, Canakkale, Turkey

*Corresponding author.

Background and aims.– Mixed features specifier has been intro-duced in the latest version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). However, characteristics of mixed depression has been argued for many years even before DSM-5. Here, we aimed to evaluate emotion regulation and affective temperament among depressive patients with and without mixed symptoms.

Methods.– Patient with major depression (n = 63) who were not on a treatment recruited for the study. Hamilton Depression Rat-ing Scale (HDRS), modified Hypomania Checklist-32 (mHCL-32), Difficulties in Emotion Adjustment Scale (DDSS) and Affective Tem-perament Scale (TEMPS-A) were applied to the participants. The collected data were evaluated with Statistical Program for Social Sciences (SPSS) version 20.

Results.– Proportion of the mixed depression was 23.8% (n = 15). There was no significant difference between patients with and without mixed depression in terms of gender, age, family history, number of disease onset, total episode and temperament scores. Non-acceptance subscale scores of DDSS was significantly higher in mixed depression group (p = 0.035). Correlation and regression analysis revealed that cyclothymic temperament scores was sig-nificantly associated with mHCL-32 scores which is related with mixity in depression (p = 0.024).

Conclusions.– Mixed features in depression is not rare as we found that one five of the patients had hypomanic symptoms during depressive episode. The association between cyclothymic temper-ament scores and mixed symptoms is in line with the idea that temperamental features are subclinic forms of mood disorders. Considering the higher non-acceptence scores and cyclothmiyc temperament scores in mixed depression, it could be concluded that mixed depression rely between pure depression and bipolar-ity. However, further prospective bigger sample sized studies are required.

Disclosure of interest.– The authors have not supplied a conflict of interest statement.

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