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Characterization of local SARS-CoV-2 isolates and pathogenicity in IFNAR(-/-) mice

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Academic year: 2021

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Figure 1. Cytopathology of SARS-Cov-2 Ank-1 isolate in Vero E6 cells. Upper row: (unstained): mock-infected cells (A), virus-infected cells (B); Lower row (crystal violet): mock-infected cells (C), D: virus-infected cells (D)
Figure 3. Phylogenetic analysis of the SARS-CoV-2 isolates. The evolutionary history was inferred using the Neighbor-Joining method ( Saitou and Nei, 1987 )
Table 2. Occurence of the 20 most frequent mutation events observed in SARS-CoV-2 genomes.
Figure 5. Hematoxlyin-eosin (A) and IHC (B) staining of respiratory epithelium in the IFNAR / mouse with prominent lung findings

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