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Ozaki Procedure: 1,100 patients with up to 12 years of follow-up

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Turkish Journal of Thoracic and Cardiovascular Surgery 2019;27(4):454

http://dx.doi.org/doi: 10.5606/tgkdc.dergisi.2019.01904

Ozaki Procedure: 1,100 patients with up to 12 years of follow-up

Ozaki prosedürü: 12 yıla varan takipte 1100 hasta

Shigeyuki Ozaki

Department of Cardiovascular Surgery, Toho University, Ohashi Medical Center, Tokyo, Japan

Correspondence: Shigeyuki Ozaki, MD. Department of Cardiovascular Surgery, Toho University, Ohashi Medical Center, 153-8515 Tokyo, Japan.

e-mail: ozakis@topaz.ocn.ne.jp

©2019 All right reserved by the Turkish Society of Cardiovascular Surgery.

Ozaki S. Ozaki Procedure: 1,100 patients with up to 12 years of follow-up. Turk Gogus Kalp Dama 2019;27(4):454

Cite this article as:

Ozaki procedure or aortic valve neo-cuspidization basically includes replacement of aortic valve cusps by three native autologous pericardial cusps. Its midterm outcomes have been published previously.[1] This video

article presents the operative technique in a stepwise method.[2]

In our clinic, this operation was performed during 12 years from April 2007 to March 2019, and more than 1,100 patients were operated. The mean age of the patients was 67.7±14.9 years. The etiology was aortic stenosis in 61.7%, aortic insufficiency in 31.1%, and both in 7.2% of the patients. The mean aortic cross-clamp and cardiopulmonary bypass times were 106.1±30.3 and 151.3±36.9, respectively. The overall survival rate is 84.6% and freedom from reoperation is 95.8% at 12 years.

This technique can be applied in patients with aor-tic stenosis, aoraor-tic regurgitation, infective endocardi-tis, and prosthetic valve endocarditis and those with non-tricuspid aortic valve with a similar method. The main strengths of the technique are the immediate superb hemodynamics after the operation and no anti-coagulation requirement postoperatively. Regarding to the operative technique, there may be some addi-tional points to be considered:

1. During the sizing of the cusps, the larger one should be selected, if one small or larger one does not exactly fit the sizer.

2. A bovine pericardium can also be used in selected patients, if native pericardium is not available. No calcification issue was experi-enced in our series.

3. A learning period usually includes the first 20 patients for such operation; therefore, the set up and technique should be supervised in the beginning.

4. If the difference between the sizing of each cusps is more than 2 mm, a new commissure should be created to prevent misalignment between the cusps.

Declaration of conflicting interests

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Funding

The authors received no financial support for the research and/or authorship of this article.

REFERENCES

1. Ozaki S, Kawase I, Yamashita H, Uchida S, Takatoh M, Kiyohara N. Midterm outcomes after aortic valve neocus-pidization with glutaraldehyde-treated autologous pericar-dium. J Thorac Cardiovasc Surg 2018;155:2379-2387. 2. Alhan C. Ozaki Procedure. Turk Gogus Kalp Dama

2019;27:451-3.

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