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• Spread by vectorcompetent Culicoides spp. • Genus Orbivirus , family Reoviridae . Bluetongue

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(1)

Bluetongue

• Genus Orbivirus, family Reoviridae.

• Sheep, goats, and cattle

(2)

• Viral infection causes endothelial damage which

initiates local microvascular thrombosis and

permeability.

• Ischemic necrosis of many tissues; edema caused

by

vascular

permeability;

and

hemorrhage

resulting from vascular damage.

• Nasal discharge, fever, focal hemorrhage on the

lips and gums, the tongue may become

edematous

and

congested

or

cyanotic

(3)

• Pathognomonic gross lesion for bluetongue is focal hemorrhage,

petechial or up to 1 cm wide × 2-3 cm long, in the tunica media at

the base of the pulmonary artery.

• Petechial hemorrhage also may be present at the base of the

aorta and in subendocardial and subepicardial locations over the

(4)

Lesions of the oral mucosa may permit the entry of pyogenic

bacteria, often normal oral flora, into the connective tissues of

the submucosa and muscle.

Purulent inflammation or cellulitis may develop in the lips,

tongue, cheek, soft palate, and pharynx.

Abscesses may form and may fistulate through the mucosa or

skin.

Usually caused by Fusobacterium necrophorum and other

(5)

Oral Necrobacillosis

Noma

Actinobacillosis

(6)

• Fusobacterium necrophorum

• Necrotizing lesions in the upper and lower alimentary tract, and liver. • Secondary invader following previous mucosal damage.

• Once established in a suitable focus, F. necrophorum proliferates, causing extensive coagulative necrosis.

• The best-known form of necrobacillary stomatitis is calf diphtheria.

• Fatal in young animals, in which extension often occurs to other organs. • In adults, oral necrobacillosis tends to remain localized to the oral

cavity, where it may complicate vesicular and ulcerative stomatitides.

(7)

• Actinobacillus lignieresii is part of the normal oral flora, and in cattle is associated with deep stomatitis.

• Typically a disease of soft tissue, spreading as a lymphangitis and usually involving the regional lymph nodes.

• The tongue is often involved ; the lesion is a pyogranuloma, appearing grossly as a nodular, firm, pale, fibrous mass a few millimeters to 1 cm in diameter, containing in the center minute yellow “sulfur” granules.

• Microscopically pyogranulomas are centered on club colonies surrounded by variable numbers of neutrophils, macrophages or giant cells.

• Lymphocytic and plasmacytic infiltrates are present in the surrounding reactive fibrous stroma or granulation tissue.

(8)

PARASITIC DISEASES OF THE ORAL CAVITY

Sarcosporidiosis and cysticercosis: striated muscles of

the tongue

Gongylonema spp.: Mucosal lining of the tongue

Trichinella spiralis : Muscles of the tongue and

mastication

Gasterophilus spp. (horse) and Oestrus ovis (sheep) :

Pharyngeal

mucosa

(focal

ulceration

and

mild

inflammation)

(9)

NEOPLASTIC AND LIKE LESIONS OF THE ORAL

CAVITY

Oral papillomatosis

Squamous cell carcinomas

Melanomas

Fibrosarcomas

Mast cell tumors

Granular cell tumors

Neuroendocrine carcinomas

Plasmacytomas

Vascular tumors

(10)

DEVELOPMENTAL ANOMALIES OF TEETH

Anodontia

(absence of teeth)

Pseudoanodontia

(Failure of the teeth to erupt from the gums)

Oligodontia

(fewer teeth than normal)

Pseudo-oligodontia

and

Pseudopoliodontia

result from failed eruption.

Polyodontia

(excessive teeth)

Heterotopic polyodontia

(an extra tooth, or teeth, outside the dental arcades)

Odontogenic cysts

(epithelium-lined cysts derived from

 epithelium associated with tooth development)

(11)

DEGENERATIVE CONDITIONS OF TEETH AND

DENTAL TISSUE

Pigmentation of the teeth (chronic fluorosis, pulpal

hemorrhages or inflammation, putrid pulpitisler, icterus,

congenital

erythropoietic

porphyria,

tetracycline,

impregnation of mineral salts with chlorophyll and

porphyrin pigments from herbage, poisoning of lead)

Dental attrition (oligodontia, diastasis dentinum),

shear mouth, wave mouth-step mouth

Odontodystrophies (Fluorine poisoning, Vitamin

(12)

INFECTIOUS AND INFLAMMATORY DISEASES OF

TEETH AND PERIODONTIUM

Supragingival plaque

Subgingival plaque

Dental calculus (tartar)

Materia alba

Dental caries

Pulpitis

Periodontal disease and gingivitis

(13)

NEOPLASTIC AND LIKE LESIONS OF THE TEETH

EPULIDES

Gingival vascular hamartoma

Pyogenic granuloma

Giant cell epulis

Fibrous epulis

Fibromatous and ossifying epulis

Acanthomatous epulis

(14)

ODONTOGENIC TUMORS

Ameloblastoma (Adamantinoma, enameloblastoma)

Calcifying epithelial odontogenic tumor

(15)

TONSILLITIS

CATARRHAL+PURULENT

TYPE

DISEASE

Gourme Distemper

Hepatitis contagiosa canis Canine parvovirus infection

CATARRHAL+NECROTIC Rinderpest / BVD-MD

 NECROTIC Necrobacillosis / Aujeszky

DIPHTHEROID Swine plaque

Panleukopenia

DIPHTHEROID+NECROTIC+HEMORRHAGIC Anthrax (Swine)

(16)

SALIVARY GLANDS

Ptyalism (increased secretion of

saliva)

Aptyalism (reduced or ceased

secretion)

Salivary calculi (sialoliths)

Dilations of the duct (ranula)

Salivary mucocele or sialocele*

Sialoadenitis (Rabies, Coryza

gangrenosa bovum, Gourme,

(17)

Esophagus

Anomalies of esophagus

Congenital duplication Segmental aplasia Esophageal atresia Esophagorespiratory fistulae

Congenital esophageal diverticula Epithelial inclusion cysts

(18)

ESOPHAGITIS

Reflux esophagitis

Erosive and ulcerative

esophagitis

Mucosal disease

Rinderpest

Malignant catarrhal fever

(19)

ESOPHAGEAL DIVERTICULA

Irregular outpouchings or herniations of the

esophageal mucosa through a defect in the

esophageal tunica muscularis.

Pulsion diverticula

(20)

Megaesophagus (esophageal ectasia)

Dilation of the esophageal lumen, and is the result of atony

and flaccidity of the esophageal muscle

Congenital idiopathic megaesophagus (CIM)

(Great Danes, German Shepherds, Irish Setters)

Secondary megaesophagus

Myastenia gravis

Administration of cholinesterase inhibitors

Hypoadrenocorticism

Giant cell axonopathy in dogs

Immun mediated polymyositis

Polyradiculoneuritis

Distemper

Systemic lupus erythematosus

Lead poisoning

(21)
(22)

NEOPLASMS OF ESOPHAGUS

Papillomas

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