阿司匹靈功效男女大不同
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發表醫師 胡朝榮 主任
發佈日期 2009/03/17
阿司匹靈功效男女
大不同
民眾衛教
-
其他衛教
作者是 朝榮週二, 17 三月 2009 22:16
美國預防服務工作小組 (US Preventive Services Task Force)建議: 阿司匹靈
(Aspirin)可以用於男性 45-79 歲之心肌梗塞一級預防, 以及女性 55-79 歲之腦梗塞
一級預防, 一級預防是指對從未罹患該疾病個體(人, 非病人)的預防, 阿司匹靈
用於無論男女之心肌梗塞或腦梗塞的二次預防(病人之疾病再發生)已是醫界的
共識及處置標準, 但阿司匹靈對心肌梗塞與腦梗塞在一次預防男女效果不同則
是值得大家注意. 此外使用阿司匹靈仍要衡量其副作用的風險, 尤其是消化道
出血的危險.
USPSTF Updates Recommendations on Aspirin for CVD Prophylaxis
The U.S. Preventive Services Task Force now recommends that aspirin be used in men to prevent MIs — and in women to prevent ischemic strokes — when these benefits outweigh the risks for gastrointestinal bleeding.
The task force considers older age and male sex as the major risk factors for gastrointestinal bleeding, followed by upper GI pain, ulcers, and NSAID use.
The recommendations, published in Annals of Internal Medicine, update the USPSTF's previous statement, released in 2002. The current statement factors in evidence from the Women's Health Study that "aspirin may have differential benefits and harms in men and women."
The task force also concludes that evidence is "insufficient" to weigh the benefits and harms of aspirin prophylaxis among people over age 79 — and that use among men under 45 or women under 55 should not be encouraged.
USPSTF's recommendations ... [will] prevent many thousands of cardiovascular events every year."
USPSTF recommendation statement in Annals of Internal Medicine (Free)
Annals of Internal Medicine editorial (Subscription required)