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Yazışma Adresi: İnönü Üniversitesi Eczacılık Fakültesi Farmasötik Teknoloji Anabilim Dalı Malatya

e-mail: naileozturk@gmail.com, naile.ozturk@hacettepe.edu.tr, naile.ozturk@inonu.edu.tr

Eğitim:

Lisans: 2006-2011

İnönü Üniversitesi, Eczacılık Fakültesi, Malatya Doktora: 2013-...

Hacettepe Üniversitesi, Farmasötik Teknoloji Doktora Programı, Ankara Akademik ve Mesleki Deneyim:

(2013-…)

Araştırma Görevlisi (ÖYP)

İnönü Üniversitesi Eczacılık Fakültesi Farmasötik Teknoloji A.D.

(2014-2018)

Araştırma Görevlisi (ÖYP)

Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü Farmasötik Teknoloji A.D.

Yayınlar

SCI ve SCI-E indekslerine giren makaleler

1. Ünal, H, Öztürk, N, Bilensoy, E. Formulation development, stability and anticancer efficacy of core-shell cyclodextrin nanocapsules for oral chemotherapy with camptothecin. (2015) Beilstein Journal of Organic Chemistry, 11, pp. 204-212.

2. Ozturk, N, Kaynak, M.S, Sahin, S. Comparison of dissolution profiles of commercially available Lamivudine tablets. (2015) Dissolution Technologies, 22 (4), pp. 38-43.

3. Gulsun, T, Ozturk, N, Kaynak, M.S, Vural, I, Sahin, S. Preparation and evaluation of furosemide containing orally disintegrating tablets by direct compression.

(2017) Pharmazie, 72 (7), pp. 389-394.

4. Ozturk, N, Kara, A, Vural, I. Evaluation of antitumor activity of a non-steroidal anti-inflammatory drug, ibuprofen, by a targeted nanoparticulate system. (2017) Latin American Journal of Pharmacy, 36 (1), pp. 44-52.

5. Sekerdag, E, Lüle, S, Bozdağ Pehlivan, S, Öztürk, N, Kara, A, Kaffashi, A, Vural, I, Işıkay, I, Yavuz, B, Oguz, K.K, Söylemezoğlu, F, Gürsoy-Özdemir, Y, Mut, M.

A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles. (2017) Journal of Controlled Release, 261, pp. 187-198.

6. Timur, S.S, Şahin, A, Aytekin, E, Öztürk, N, Polat, K.H, Tezel, N, Gürsoy, R.N, Çalış, S. Design and in vitro evaluation of tenofovir-loaded vaginal gels for the prevention of HIV infections. (2018) Pharmaceutical Development and Technology, 23 (3), pp. 301-310.

7. Kara, A, Ozturk, N, Esendagli, G, Ozkose, U.U, Gulyuz, S,Yilmaz, O, Telci, D, Bozkir, A, Vural, I. Development of novel self-assembled polymeric micelles from partially hydrolysed poly(2-ethyl-2-oxazoline)-co-PEI-b-PCL block copolymer as non-viral vectors for plasmid DNA in vitro transfection. (2018) Artificial Cells,

Nanomedicine and Biotechnology, https://doi.org/10.1080/21691401.2018.1491478.

Kitap Bölümü

1. Kara, A, Ozturk, N, & Vural, I. In Vitro CNS Models. (2017) In Nanotechnology Methods for Neurological Diseases and Brain Tumors (pp. 151-185).

Bildiriler

Poster Bildirileri (Uluslararası)

1. Geneş M, Öztürk N, Kaynak M.S, Sahin S. “Comparision of Dissolution Profiles of Two Commercially Available Furosemide Tablets” MAGUM-DRD 2011, International Symposium on Drug Research and Development “From Chemistry to Medicine”, 27-29 May, 2011, Antalya-Turkey.

2. Öztürk N, Kaynak M.S, Şener M, Erdemoğlu M, Şahin S. “ Investigation Of Dissolution Characteristics Of Amorphous Furosemide Prepared By Ball Milling Technique’’ International Multidiciplinary Symposium on Drug Research &

Development 28-30 November 2013, Kervansaray Hotel Lara, Antalya, Turkey 3. Öztürk N, Kaynak M.S, Büyktuncel S.E, Sahin S. “Development And Validation

Of A Rp-Hplc Method For Determınatıon Of Lamivudine From Drug Dissolution Studies’’ International Multidiciplinary Symposium on Drug Research &

Development 28-30 November 2013, Kervansaray Hotel Lara, Antalya, Turkey 4. Ozturk N, Kara A, Vural I. “Preparation And Cytotoxic Evaluation Of Antibody

Targeted Ibuprofen Loaded-Plga Nanoparticles’’, 17th International Pharmaceutical Technology Symposium, 8-10 September 2014, Antalya, Turkey 5. KaraA, AnutaV, Barbuceanu S.F, Nitulescu G.M, Ozturk N, Pehlivan S, SahinS,

Sarisozen C, Uivarosi V, Velescu B.S, Vural I. “Cytotoxicity Of Some New Ruthenium (III) Complexes With Improved Solubility Conjugated With Quinolone’’, 17th International Pharmaceutical Technology Symposium, 8-10 September 2014, Antalya, Turkey

6. Ozturk N, Kara A, Vural I. “Investigate the Effect Of Ibuprofen And Paclitaxel Combination To Determine The Cytotoxicity In L929 Fibroblast Cells’’, 17th International Pharmaceutical Technology Symposium, 8-10 September 2014, Antalya, Turkey

7. Ozturk N, Gulsun Inal T, Sahin S, Vural I. “Comparison Of Furosemide Nanocrystals And Nanosuspensions In Terms Of Solubility And Permeability’’, 17th International Pharmaceutical Technology Symposium, 8-10 September 2014, Antalya, Turkey

8. Ozturk N, Kara A, Vural I. “Ibuprofen Loaded Nanoparticles as an Anticancer Agent: Cytotoxicity on MCF-7 Cell Line’’ AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA

9. Ozturk N, Kara A, Vural I. “ The combined treatment of nonsteroidal anti-inflammatory drug ibuprofen and paclitaxel to suppress the viability of mcf-7 breast cancer cell line’’, AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA

10. Gulsun Inal T, Ozturk N, Pehlivan S, Sahin S, Vural I. “ Effect of Milling Time on the Formulation Parameters of Nanosuspensions’’, AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA

11. Gulsun Inal T, Ozturk N, Kaynak M.S, Sahin S, Vural I. “ Preparation and Evaluation of Furosemide Containing Orally Disintegrating Tablets by Direct Compression’’, AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA

12. Ozturk N, Kara A, Gulsun Inal T, Pehlivan S, Vural I, Sahin S. “ Effect of Precipitation Inhibitors on Supersaturation and Solubility of Furosemide’’, AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA 13. Ozturk N, Gulsun Inal T, Kaynak M.S, Vural I, Sahin S. “ Development of Orally

Disintegrating Tablets Containing Olmesartan Medoxomil and Amlodipine Besylate’’, AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego, CA, USA

14. Ozturk N, Kara A, Vural I. “In Vitro Characterization And Evaluation Of PLA Nanoparticles Loaded With Telmisartan” GPSS 2015, Antalya, Turkey, 12-15 November 2015.

15. Kara A, Ozturk N, Vural I. “Determination Of Cytotoxicity Of Dexamethasone Sodium Phosphate On MCF-7 And L929 Cell Lines” GPSS 2015, 12-15 November 2015, Antalya, Turkey.

16. Ozturk N, Kara A, Ozkose UU, Yilmaz O, Bozkır A, Vural I. “Polymeric Micelles Based On Poly (2-Ethyl-2-Oxazoline) As Drug Carriers” GPSS 2015, 12-15 November 2015, Antalya, Turkey.

17. Kara A, Ozturk N, Gulyuz S, Yilmaz O, Bozkır A, Vural I. “The Effect Of Preparation Method On Size Of Poly (2-Ethyl-2-Oxazoline)(Petox)-B-Polycaprolactone (PCL) Polymeric Micelles” GPSS 2015, 12-15 November 2015, Antalya, Turkey.

18. Sahin G, Ozturk N, Vural I. “Development and Evaluation Of Orally Disintegrating Tablets Of Fosinopril Sodium By Direct Compression Method”

GPSS 2015, 12-15 November 2015, Antalya, Turkey.

19. Ozturk N, Kara A, Vural I. ‘’Telmisartan loaded nanoparticles prepared by emulsion solvent evaporation technique’’, 18th IPTS, 18-21 September 2016, Antalya, Turkey.

20. Ozturk N, Kara A, Vural I. ‘’Investigation of anti-tumor effect of telmisartan loaded poly(d,l-lactide) nanoparticles on mcf-7 cells’’, 18th IPTS, 18-21 September 2016, Antalya, Turkey.

21. Kara A, Ozturk N, Vural I. ‘’In vitro evaluation of dexamethasone sodium phosphate (dex-np) loaded chitosan nanoparticles as an antitumor agent on mcf-7 cell line’’, 18th IPTS, 18-21 September 2016, Antalya, Turkey.

22. Kara A, Ozturk N, Gulyuz S, Ozkose U. U, Vural I, Yılmaz O, Bozkır A. ‘’Micellar characteristics of poly-(2-ethyl-2-oxazoline)-co-poly(ethylenimine)- block-poly(ɛ-caprolactone) (petox-co-peı-b-pcl) block copolymers of different hydrolysis degrees of PEtOx’’, 18th IPTS, 18-21 September 2016, Antalya, Turkey.

23. Sahin G, Ozturk N, Vural I. ‘’Dissolution profiles of fosinopril sodium orodispersible tablets and orodispersible films’’, 18th IPTS, 18-21 September 2016, Antalya, Turkey.

24. Kara A, Ozturk N, Ozkose UU, Bolat ZB, Yilmaz O, Telci D, Bozkir A, Vural I.

“Evaluation Of Morphological And Physical Characteristics Of Poly (2-Ethyl-2-

Oxazoline)-Co-Poly(Ethylenimine)-Block-Poly(Ɛ-Caprolactone)(Petox-Co-Peı-B-Pcl) Polymeric Micelle As A Gene Delivery Agent”, AAPS National Biotechnology Conference, 1-3 May 2017, San Diego, USA.

25. Kara A, Ozturk N, Esendagli G, Bolat ZB, Gulyuz S, Telci D, Yilmaz O, Bozkir A, Vural I. “Novel Polymeric Micelles Based On Poly-(2-Ethyl-2-Oxazoline)-Co-Poly(Ethylenimine)-Block-Poly(Ɛ-Caprolactone) Petox-Co-Pei-B-Pcl Block Copolymer W,th Various Hydrolysis Degree To Evaluate The Effect Of Transfection Efficiency On Mcf-7 Cells”, AAPS National Biotechnology Conference, 1-3 May 2017, San Diego, USA.

26. Kara A, Ozturk N, Vural I. “Development And Characterization Of Novel Co-Delivery System Based On Dexamethasone Sodium Phosphate (Dex-Np) Loaded Chitosan With Plasmid DNA”, GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

27. Al-Heibshy FNS, Basaran E, Ozturk N, Demirel M, "Enhancement Of Solubility Of Rosuvastatin Calciumby Complexation With Methyl-Betacyclodextrin", GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

28. Al-Heibshy FNS, Basaran E, Ozturk N, Demirel M. "Inclusion Complexes Of Rosuvastatin Calcium Withsulfobutylether-Beta-Cyclodextrin (Captisol®)", GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

29. Ozturk N, Pezik E, Kara A, Vural I. “Pullulan Based Orally Disintegrating Films Of Telmisartan”, GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

30. Pezik E, Ozturk N, Vural I. “Orally Disintegrating Tablets Of Telmisartan;

Formulation Development And Evaluation”, GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

31. Sekerdag E, Lüle S, Bozdağ Pehlivan S, Öztürk N, Kara A, Kaffashi A, Vural I, Işıkay I, Yavuz B, Oguz K.K, Söylemezoğlu F, Gürsoy-Özdemir Y, Mut M. “The Biodistribution Of Farnesylthiosalicylic Acid Incorporated Hybrid Nanoparticles Following Intranasal Administration In Rats”, GPSS2017: 2nd Gazi Pharma Symposium Series, 11-13 October 2017, Ankara, Turkey.

32. Ozturk N, Kara A, Ozkose U.U Gulyuz S,Yilmaz O, Bozkir A, Vural I.

“Preparation and Characterization of Docetaxel Loaded Polymeric Micelles” 19th IPTS, 17-19 September 2018, Antalya, Turkey.

33. Ozturk N, Kara A, Ozkose U.U Gulyuz S ,Yilmaz O, Bozkir A, Vural I. “In Vitro Evaluation of pH Sensitive Doxorubicin Loaded Micelles” 19th IPTS, 17-19 September 2018, Antalya, Turkey.

34. Ozturk N, Uğur A.B, Vural I. Çetin M. “Investigation of Cytotoxic Effects of Daidzein and Levetiracetam on RG2 Glioma Cell Line” 19th IPTS, 17-19 September 2018, Antalya, Turkey.

35. Kara A, Ozturk N, Esendagli G, Ozkose U.U, Gulyuz S, Bolat Z, Yilmaz O, Telci D, Bozkir A, Vural I. “Apoptic Gene Therapy by Novel Developed Partially Hydrolysed PEtOx Based Micellar Nanocarriers on MCF-7 Breast Cancer Cells”

19th IPTS, 17-19 September 2018, Antalya, Turkey.

36. Kara A, Ozturk N, Gulyuz S, Ozkose U.U, , Bolat Z, Yilmaz O, Telci D, Bozkir A, Vural I. “Evaluation of Stealth Properties of PEtOx Based Micelle/Gene

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